Four Glove Dispensing isolator for expermiments with highly active and cytotoxic compounds.
Description: The four-glove isolator is a safe chamber, with controlled environment for the weighing and handling of potent drug compounds.
Technical specifications: The Isolator has been designed to offer containment to a working OEL (Occupational Exposure Limit) of less than 0.1Jgrams/m³ time weighted average over an 8hr operational period (TWA).
The Isolator is designed to offer an internal air cleanliness of Class 8 as described in ISO 14644-7 and the test pass criteria is a leakage rate of ≤0.25% vol/hr and is in line with Class 2 classification of ISO 14644-7.
- Internal Environment: – Main Chamber: -100Pa +/- 10%.
- Air Changes per hour: Nominal 20 during normal operating conditions giving ISO 8.
- Glove Breach Velocity: >0.5m/sec.
- Exhaust System: Max air flow 108m3/hr.
- Inlet HEPA Filter: H14 Canister (safe-change when changed into Isolator). 99.995% efficient @ 3Jm particle size.
- Exhaust HEPA Filter: 1st Stage – H14 HEPA & 2nd Stage – H14 HEPA mounted within Push-Push Safe Change housing 99.995% efficient @ 3Jm particle size.
Applications:
Pharmaceutical Manufacturing: In pharmaceutical manufacturing, especially for the production of potent drugs or active pharmaceutical ingredients (APIs), a 4-glove isolator can be used for containment. It helps in preventing cross-contamination and ensures the safety of both the product and the operator.
Biotechnology Research: In research laboratories working with hazardous biological materials such as viruses, bacteria, or genetically modified organisms (GMOs), a 4-glove isolator provides a secure environment for manipulation and experimentation. It minimizes the risk of exposure to harmful agents.
Sterile Compounding: In compounding pharmacies and hospital pharmacies, a 4-glove isolator can be utilized for sterile compounding of medications. It helps in maintaining aseptic conditions, preventing contamination, and ensuring the safety and efficacy of compounded drugs.