Computed Tomography (CT)
Computed Tomography (CT) is based on the reconstruction of 2D X-ray images captured at different angles to generate a detailed 3D view of the subject. CT imaging is typically used to provide vital contextual information for other modalities as well as for specific studies into bone density, contrast agents, implantation and regenerative technologies. Our Albira system uses dedicated beds for rats and mice with incorporated gas anesthesia. The Albira software suite automates the reconstruction process, while the PMOD software suite enables advanced analyses and the export of data into popular formats such as DICOM.
Customer benefits
We have SOPs and ISO9001 certification. We also have specialist technicians for the use of the equipment.
This service is essential to:
- Dentistry and bone regeneration studies
- Contextual/anatomical imaging in conjunction with other modalities
- Bone density analysis
- Implantation studies
Target customer
Any company or research group interested in:
- Phantom-based measurement of reagent densities (e.g. as part of the characterization of X-ray/CT-based contrast agents)
- Bone-density measurements based on calibration using a calcium hydroxyapatite phantom.
- Image processing, analysis and quantification services, including specialized packages such as PMOD, FIJI and BoneJ.
- Advanced custom 3D visualizations using the Imaris software package.
- Close integration with other BIONAND units for associated animal handling and histology services.
References
- Caro C, Gámez F, Quaresma P, Páez-Muñoz JM, Domínguez A, Pearson JR, Pernía Leal M, Beltrán AM, Fernandez-Afonso Y, De la Fuente JM, Franco R, Pereira E, García-Martín ML. Fe3O4-Au Core-Shell Nanoparticles as a Multimodal Platform for In Vivo Imaging and Focused Photothermal Therapy. Pharmaceutics. 2021 Mar 20;13(3):416. doi: 10.3390/pharmaceutics13030416. PMID: 33804636; PMCID: PMC8003746.
- Christou E, Pearson JR, Beltrán AM, Fernández-Afonso Y, Gutiérrez L, de la Fuente JM, Gámez F, García-Martín ML, Caro C. Iron-Gold Nanoflowers: A Promising Tool for Multimodal Imaging and Hyperthermia Therapy. Pharmaceutics. 2022 Mar 14;14(3):636. doi: 10.3390/pharmaceutics14030636. PMID: 35336012; PMCID: PMC8955043.