Cell cultures
The cell culture service plays a pivotal role in the realm of biomedical and pharmaceutical research, as well as in the broader fields of cellular and molecular biology. It provides specialized support for the development, production, and characterization of cell therapies tailored for preclinical trials. With a focus on mesenchymal stem cells (MSCs), the service encompasses the entire spectrum of cell culture activities, including isolation, expansion, and thorough characterization of these crucial cellular components. Additionally, the service extends its offerings to include essential assays such as proliferation, viability, and cytotoxicity assessments, all of which are indispensable in the rigorous evaluation of potential therapies during preclinical trials.
Customer benefits
U14 Cell Therapy Unit offers researchers precision, efficiency, and expertise, streamlining experiments. With stringent quality control, ISO 9001-2015 and GLP compliant, tailored solutions, and access to advanced equipment, researchers can focus on innovation and core objectives, driving scientific progress forward.
Target customer
This service is essential for organizations involved in Research and Development, including pharmaceutical companies, academic institutions for biomedical research, biotechnology firms for bioprocessing, and regulatory agencies for in vitro studies. Cell Culture service empowers researchers and stakeholders with the tools and insights necessary to advance the frontiers of regenerative medicine and therapeutic innovation.
Additional information
Selected references:
- de Pedro, Maria Ageles; Pulido, Maria; Álvarez, Veronica; Marinaro, Federica; Marchena, Ana Maria; Sanchez-Margallo, Francisco Miguel; Casado, Javier G.; Lopez, Esther. 2023. Menstrual blood-derived stromal cells: insights into their secretome in acute hypoxia conditions. MOLECULAR MEDICINE. SPRINGER. 29-1. ISSN 1076-1551. https://doi.org/10.1186/s10020-023-00646-1
- Cristobal JI; Duque, FJ; Uson-Casaus J; Barrera R; López E; Perez-Merino EM. 2022. Complete Blood Count-Derived Inflammatory Markers Changes in Dogs with Chronic Inflammatory Enteropathy Treated with Adipose-Derived Mesenchymal Stem Cells Animals. MDPI. 12-20. ISSN 2076-2615. https://doi.org/10.3390/ani12202798
- Marinaro, Federica; Silva, Joana M; Barros, Alexandre A; et al; Lopez, Esther. 2021. A Fibrin Coating Method of Polypropylene Meshes Enables the Adhesion of Menstrual Blood-Derived Mesenchymal Stromal Cells: A New Delivery Strategy for Stem Cell-Based Therapies.International journal of molecular sciences. MDPI. 22-24. ISSN 1422-0067. WOS (0) https://doi.org/10.3390/ijms222413385
- de Pedro, Maria Angeles; Gomez-Serrano, Maria; Marinaro, Federica; et al; Lopez, Esther (AC); Casado, Javier G.(4/10). 2021. IFN-Gamma and TNF-Alpha as a Priming Strategy to Enhance the Immunomodulatory Capacity of Secretomes from Menstrual Blood-Derived Stromal Cells INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. MDPI. 22-22. ISSN 1422-0067. WOS (0) https://doi.org/10.3390/ijms222212177
- López E; Blazquez R; Marinaro F; et al; Casado JG. 2019. The Intrapericardial Delivery of Extracellular Vesicles from Cardiosphere-Derived Cells Stimulates M2 Polarization during the Acute Phase of Porcine Myocardial Infarction. STEM CELL REVIEWS AND REPORTS. SPRINGER. 16-3, pp.626-626. ISSN 2629-3269. https://doi.org/10.1007/s12015-019-09926-y