Publications 2021

U01, U29, U18 Eric Voltà-Durán, Naroa Serna, Laura Sánchez-García, Anna Aviñó, Julieta M. Sánchez, Hèctor López-Laguna, Olivia Cano-Garrido, Isolda Casanova, Ramón Mangues, Ramon Eritja, Esther Vázquez, Antonio Villaverde, Ugutz Unzueta, Design and engineering of tumor-targeted, dual-acting cytotoxic nanoparticles, Acta Biomaterialia, Volume 119, 2021,Pages 312-322 https://doi.org/10.1016/j.actbio.2020.11.018.

U06, U01, U03, U20 – Josep Merlo-Mas, Judit Tomsen-Melero, José-Luis Corchero, Elisabet González-Mira, Albert Font, Jannik N. Pedersen, Natalia García-Aranda, Edgar Cristóbal-Lecina, Marta Alcaina-Hernando, Rosa Mendoza, Elena Garcia-Fruitós, Teresa Lizarraga, Susanne Resch, Christa Schimpel, Andreas Falk, Daniel Pulido, Miriam Royo, Simó Schwartz, Ibane Abasolo, Jan Skov Pedersen, Dganit Danino, Andreu Soldevila, Jaume Veciana, Santi Sala, Nora Ventosa, Alba Córdoba, “Application of Quality by Design to the robust preparation of a liposomal GLA formulation by DELOS-susp method”, The Journal of Supercritical Fluids, Volume 173, 2021, 105204, https://doi.org/10.1016/j.supflu.2021.105204.

U06, U01, U03, U20 – Judit Tomsen-Melero, Solène Passemard, Natalia García-Aranda, Zamira Vanessa Díaz-Riascos, Ramon González-Rioja, Jannik Nedergaard Pedersen, Jeppe Lyngsø, Josep Merlo-Mas, Edgar Cristóbal-Lecina, José Luis Corchero, Daniel Pulido, Patricia Cámara-Sánchez, Irina Portnaya, Inbal Ionita, Simó Schwartz, Jaume Veciana, Santi Sala, Miriam Royo, Alba Córdoba, Dganit Danino, Jan Skov Pedersen, Elisabet González-Mira, Ibane Abasolo, and Nora Ventosa. Impact of Chemical Composition on the Nanostructure and Biological Activity of α-Galactosidase-Loaded Nanovesicles for Fabry Disease Treatment, ACS Appl. Mater. Interfaces 2021, 13, 7, 7825–7838 ( https://doi.org/10.1021/acsami.0c16871).

U01-Naroa Serna, José V. Carratalá, Oscar Conchillo-Solé, Carlos Martínez-Torró, Ugutz Unzueta, Ramón Mangues, Neus Ferrer-Miralles, Xavier Daura, Esther Vázquez, and Antonio Villaverde. Antibacterial Activity of T22, a Specific Peptidic Ligand of the Tumoral Marker CXCR4 Pharmaceutics 13, no. 11: 1922. [DOI]

U10- Tania B. Lopez-Mendez, Edorta Santos-Vizcaino, Jose Luis Pedraz, Gorka Orive, Rosa Maria Hernandez, “Cell microencapsulation technologies for sustained drug delivery: Latest advances in efficacy and biosafety,” Journal of Controlled Release, Volume 335, 10 July 2021, Pages 619-636 https://doi.org/10.1016/j.jconrel.2021.06.006

U25- Pilar Calero-Pérez, Shuang Wu,Carles Arús, Ana Paula Candiota. System-Related Changes in Preclinical GL261 Glioblastoma under TMZ Treatment: Explaining MRSI-Based Nosological Imaging Findings with RT-PCR Analyses Cancers 2021, 13(11), 2663 [DOI]

U02 Montagut, E.J., Marco, M.P. Biological and clinical significance of quorum sensing alkylquinolones: current analytical and bioanalytical methods for their quantification. Anal Bioanal Chem 413, 4599–4618 (2021).[DOI]

U10, U12, U29 – Sainz-Ramos M, Villate-Beitia I, Gallego I, AL Qtaish N, Menéndez M, Lagartera L, Grijalvo S, Eritja R, Puras G, Pedraz JL. Correlation between Biophysical Properties of Niosomes Elaborated with Chloroquine and Different Tensioactives and Their Transfection Efficiency. Pharmaceutics. 2021; 13(11):1787. [DOI]

U09–Aina, S., Villacampa, B., Bernechea, M., Earth-abundant non-toxic perovskite nanocrystals for solution processed solar cells, Mater. Adv., 2021, 2, 4140 [DOI]

U28–Youssef, L., Simoes, R. V., Miranda, J., Garcia-Martin, M. L., Paules, C., Crovetto, F., Amigo, N., Canellas, N., Gratacos, E. & Crispi, F. Paired maternal and fetal metabolomics reveal a differential fingerprint in preeclampsia versus fetal growth restriction. Sci Rep 11, 14422, (2021). [DOI]

U28–Gomez-Gonzalez, E., Caro, C., Martinez-Gutierrez, D., Garcia-Martin, M. L., Ocana, M. & Becerro, A. I. Holmium phosphate nanoparticles as negative contrast agents for high-field magnetic resonance imaging: Synthesis, magnetic relaxivity study and in vivo evaluation. J Colloid Interface Sci 587, 131-140, (2021). [DOI]

U28–Fernandez-Alvarez, F., Caro, C., Garcia-Garcia, G., Garcia-Martin, M. L. & Arias, J. L. Engineering of stealth (maghemite/PLGA)/chitosan (core/shell)/shell nanocomposites with potential applications for combined MRI and hyperthermia against cancer. J Mater Chem B 9, 4963-4980, (2021).. [DOI]

U28–Caro, C., Paez-Muñoz, J. M., Beltrán, A. M., Pernia Leal, M. & García-Martín, M. L. PEGylated Terbium-Based Nanorods as Multimodal Bioimaging Contrast Agents. ACS Applied Nano Materials 4, 4199-4207, (2021). [DOI]

U28–Caro, C., Gámez, F., Quaresma, P., Páez-Muñoz, J. M., Domínguez, A., Pearson, J. R., Pernía Leal, M., Beltrán, A. M., Fernandez-Afonso, Y., De la Fuente, J. M., Franco, R., Pereira, E. & García-Martín, M. L. Fe3O4-Au Core-Shell Nanoparticles as a Multimodal Platform for in Vivo Imaging and Focused Photothermal Therapy. Pharmaceutics 13, 416, (2021). [DOI]

U28–Caro, C., Avasthi, A., Paez-Muñoz, J. M., Pernia Leal, M. & García-Martín, M. L. Passive targeting of high-grade gliomas via the EPR effect: a closed path for metallic nanoparticles? Biomaterials Science, (2021). [DOI].

U28–Vladimir Stamenkovic, Daniel Collado, Ezequiel Perez-Inestrosa   Photophysical properties and bioimaging application of an aminonaphthalimide-squaraine non-conjugated system spectrochimica Acta Part A: Molecular And Biomolecular Spectroscopy, 2022, 267 part 2, 120546. [DOI]

U28–Anjara Morgado, Francisco Najera, Anna Lagunas, Josep Samitier, Yolanda Vida And Ezequiel Perez-Inestros Lightly congested amino terminal dendrimers. Amide-based stable structures with large-scale synthesis Polymer Chemistry,  2021, 12 (36), 5168 – 5177. [DOI]

U28–Sergio Gámez‐Valenzuela, David Neusser, Carlos Benitez‐Martin, Francisco Najera, Juan A. Guadix, Carlos Moreno‐Yruela, Belén Villacampa, Rocío Ponce Ortiz, Sabine Ludwigs, Raquel Andreu, M. Carmen Ruiz Delgado V‐shaped pyranylidene/triphenylamine‐based chromophores with enhanced photophysical, electrochemical and nonlinear optical properties  Materials Advances, 2021, 2, 4255-4263.

U28–Amene Tesfaye, Alba Rodríguez-Nogales, Sara Benedé, Tahía D. Fernández, Juan L. Paris, Maria J. Rodriguez, Isabel M. Jiménez-Sánchez, Gador Bogas, Cristobalina Mayorga, María J. Torres, María I. Montañez  Nanoarchitectures for efficient ige cross-linking on effector cells to study amoxicillin  Allergy.  2021;00:1–11. [DOI]

U27–Palacios, S., Cygankiewicz, I., Bayés de Luna, A. et al. Periodic repolarization dynamics as predictor of risk for sudden cardiac death in chronic heart failure patients. Sci Rep 11, 20546 (2021). [DOI]

U20–Marwa M Abu-Serie, Fernanda Andrade, Patricia Cámara-Sánchez, Joaquín Seras-Franzoso, Diana Rafael, Zamira V Díaz-Riascos, Petra Gener, Ibane Abasolo, Simó Schwartz Jr Pluronic F127 micelles improve the stability and enhance the anticancer stem cell efficacy of citral in breast cancer. PMID: 34160295 [DOI]

U10, U14– Ziani K, Espona-Noguera A, Crisóstomo V, Casado JG, Sanchez-Margallo FM, Saenz-Del-Burgo L, Ciriza J, Pedraz JL. Characterization of encapsulated porcine cardiosphere-derived cells embedded in 3D alginate matrices. Int J Pharm. 2021 Apr 15;599:120454.[DOI]

U09–Teresa Alejo, Laura Usón, Guillermo Landa, Martin Prieto, Cristina Yus Argón, Sara García-Salinas, Ricardo de Miguel, Ana Rodríguez-Largo, Silvia Irusta, Victor Sebastián, Gracia Mendoza and Manuel Arruebo. Nanogels with High Loading of Anesthetic Nanocrystals for Extended Duration of Sciatic Nerve Block, ACS Appl. Mater. Interfaces, 13, 15, 17220–17235. 2021 April 6. [DOI]

U25–Javier García-Pardo, Fernando Novio, Fabiana Nador, Ivana Cavaliere, Salvio Suárez-García, Silvia Lope-Piedrafita, Ana Paula Candiota, Jordi Romero-Gimenez, Beatriz Rodríguez-Galván, Jordi Bové, Miquel Vila, Julia Lorenzo, and Daniel Ruiz-Molina, Bioinspired Theranostic Coordination Polymer Nanoparticles for Intranasal Dopamine Replacement in Parkinson’s Disease. ACS Nano 2021, 15, 5, 8592–8609, May 2021. [DOI]

U26- Iris Garrido-Cano, Luis Pla, Sara Santiago-Felipe, Soraya Simón, Belen Ortega, Begoña Bermejo, Ana Lluch, Juan Miguel Cejalvo , Pilar Eroles, and Ramón Martínez-Máñez. Nanoporous Anodic Alumina-Based Sensor for miR-99a-5p Detection as an Effective Early Breast Cancer Diagnostic Tool ACS Sensors 2021 6 (3), 1022-1029 [DOI]

U29- Clua A, Fàbrega C, García-Chica J, Grijalvo S, Eritja R. Parallel G-quadruplex Structures Increase Cellular Uptake and Cytotoxicity of 5-Fluoro-2′-deoxyuridine Oligomers in 5-Fluorouracil Resistant Cells. Molecules. 2021; 26(6):1741. [DOI]

U12– Mónica Cicuéndez, Andreia Coimbra, Joana Santos, Helena Oliveira, Miguel Ayán−Varela, Juan Ignacio. Paredes, Sílvia Villar−Rodil, Mercedes Vila, and Virgília Sofia Silva Cytotoxicity of Nucleotide-Stabilized Graphene Dispersions on Osteosarcoma and Healthy Cells: On the Way to Safe Theranostics Agents  ACS Applied Bio Materials Article ASAP. [DOI]

U17– Martínez-Martínez D, Toledo Lobo MV, Baquero P, Ropero S, Angulo JC, Chiloeches A, Lasa M, Downregulation of Snail by DUSP1 Impairs Cell Migration and Invasion through the Inactivation of JNK and ERK and Is Useful as a Predictive Factor in the Prognosis of Prostate Cancer Cancers 2021, 13, 1158. [DOI]

U17– Yuan K,  Jurado‐Sánchez B,  Escarpa A, Dual‐Propelled Lanbiotic Based Janus Micromotors for Selective Inactivation of Bacterial Biofilms. Angewandte Chemie (2021) [DOI] 

U17– Alcalde-Estévez, E., Sosa, P., Asenjo-Bueno, A. et al. Uraemic toxins impair skeletal muscle regeneration by inhibiting myoblast proliferation, reducing myogenic differentiation, and promoting muscular fibrosis. Sci Rep 11, 512 (2021). [DOI] 

U27 – Pelaez-Coca, M D; Hernando, A; Lozano, M T; Sanchez, C; Izquierdo, D; Gil, E  Photoplethysmographic Waveform and Pulse Rate Variability Analysis in Hyperbaric Environments. IEEE Journal of Biomedical and Health Informatics, 2021. [DOI]

U27 – Palmieri F, Gomis P, Ruiz JE, Ferreira D, Martín-Yebra A, Pueyo E, Martínez JP, Ramírez J, Laguna P. Nonlinear T-Wave Time Warping-Based Sensing Model for Non-Invasive Personalised Blood Potassium Monitoring in Hemodialysis Patients: A Pilot Study. Sensors. 2021; 21(8):2710. [DOI]

U27 – Palmieri E, Gomis P, Ferreira D, Ruiz JE, Bergasa B, Martín-Yebra A, Bukhari HA, Pueyo E, Martínez JP, Ramírez J, Laguna P. Monitoring blood potassium concentration in hemodialysis patients by quantifying T-wave morphology dynamics Sci Rep 11, 3883 (2021). [DOI]  

U27 -H. A. Bukhari et al., Characterization of T Wave Amplitude, Duration and Morphology Changes During Hemodialysis: Relationship with Serum Electrolyte Levels and Heart Rate”  IEEE Transactions on Biomedical Engineering, [DOI] 

U20 – Gustavo Carreño, Alfredo Pereira, Fabián Ávila-Salas, Adolfo Marican, Fernanda Andrade, Maria Mercé Roca-Melendres, Oscar Valdés, Sekar Vijayakumar, Simó Schwartz, Ibane Abasolo, Diana Rafael, Esteban F. Durán-Lara, Development of “on-demand” thermo-responsive hydrogels for anti-cancer drugs sustained release: Rational design, in silico prediction and in vitro validation in colon cancer models, Materials Science and Engineering: C, Volume 131, 2021, 112483, ISSN 0928-4931, https://doi.org/10.1016/j.msec.2021.112483.

U20 – Yolanda Fernández, Julie Movellan,Laia Foradada, Vanessa Giménez, Natalia García-Aranda, Sandra Mancilla, Ana Armiñán, Sven Even Borgos, Astrid Hyldbakk, Anna Bogdanska, Oliviero L. Gobbo, Adriele Prina-Mello, Jessica Ponti, Luigi Calzolai, Oleksandr Zagorodko, Elena Gallon, Amaya Niño-Pariente, Alison Paul, Simó Schwartz Jr, Ibane Abasolo, María J. Vicent In Vivo Antitumor and Antimetastatic Efficacy of a Polyacetal-Based Paclitaxel Conjugate for Prostate Cancer Therapy. Adv Healthc Mater. 2021 Oct 27;e2101544. doi: 10.1002/adhm.202101544.

U20 – Diana Rafael, Maria Mercè Roca Melendres, Fernanda Andrade, Sara Montero, Francesc Martinez-Trucharte, Mireia Vilar-Hernandez, Esteban Francisco Durán-Lara, Simó Schwartz Jr, Ibane Abasolo,
Thermo-responsive hydrogels for cancer local therapy: Challenges and state-of-art, International Journal of Pharmaceutics, Volume 606, 2021,
120954, ISSN 0378-5173, https://doi.org/10.1016/j.ijpharm.2021.120954.

U20 – Marwa M Abu-Serie , Fernanda Andrade, Patricia Cámara-Sánchez, Joaquin Seras-Franzoso, Diana Rafael, Zamira V Díaz-Riascos, Petra Gener, Ibane Abasolo, Simó Schwartz Jr Pluronic F127 micelles improve the stability and enhance the anticancer stem cell efficacy of citral in breast cancer. Nanomedicine VOL. 16, NO. 17. 2021 Jul;16(17):1471-1485. doi: 10.2217/nnm-2021-0013.

U20 – Eva Espinosa-Cano, Miguel Huerta-Madroñal, Patricia Cámara-Sánchez, Joaquin Seras-Franzoso, Simo Schwartz, Ibane Abasolo, Julio San Román, Maria Rosa Aguilar, Hyaluronic acid (HA)-coated naproxen-nanoparticles selectively target breast cancer stem cells through COX-independent pathways, Materials Science and Engineering: C, Volume 124, 2021, 112024, ISSN 0928-4931, https://doi.org/10.1016/j.msec.2021.112024.

U20 – Fernanda Andrade, Diana Rafael, Mireia Vilar-Hernández, Sara Montero, Francesc Martínez-Trucharte, Joaquin Seras-Franzoso, Zamira V. Díaz-Riascos, Ana Boullosa, Natalia García-Aranda, Patricia Cámara-Sánchez, Diego Arango, Marika Nestor, Ibane Abasolo, Bruno Sarmento, Simó Schwartz, Polymeric micelles targeted against CD44v6 receptor increase niclosamide efficacy against colorectal cancer stem cells and reduce circulating tumor cells in vivo, Journal of Controlled Release, Volume 331, 2021, 198-212, ISSN 0168-3659, https://doi.org/10.1016/j.jconrel.2021.01.022.

U08 – Masvidal-Codina E,  Smith TM, Rathore D, Gao Y, Illa X, Prats-Alfonso, E, Del Corro E, Calia AB, Rius G, Martin-Fernandez I, Guger C,  Reitner P, Villa R, Garrido JA, Guimerà-Brunet A, Wykes R, Characterization of optogenetically-induced cortical spreading depression in awake mice using graphene micro-transistor arrays  J. Neural Eng. 2021 82021 18 055002 [DOI]

U08 – Garcia-Cortadella R, Schwesig G, Jeschke C, Illa X, Gray AL, Savage S, Stamatidou E, Schiessl I, Masvidal-Codina E, Kostarelos K, Guimerà-Brunet A, Sirota A, Garrido JA. Graphene active sensor arrays for long-term and wireless mapping of wide frequency band epicortical brain activity Nature Communications 12 (2021) 211 [DOI]

U08 – Nguyen D, Valet M, Dégardin J, Boucherit L, Illa X, de la Cruz J, del Corro E, Bousquet J, Garrido JA, Hébert C and Picaud S. Novel Graphene Electrode for Retinal Implants: An in vivo Biocompatibility Study. Frontiers in Neuroscience 15 (2021) 615256 [DOI]

U08 – Marrero D, Pujol-Vila F, Vera D, Gabriel G, Illa X,  Elizalde-Torrent A, Alvarez M, Villa R, Gut-on-a-chip: Mimicking and monitoring the human intestine. Biosensors and Bioelectronics. Volume 181, 1 June 2021, 113156. [DOI] 

U08 – Vera D, García-Díaz M, Torras N, Alvarez M, Villa R, Martínez E. Engineering Tissue Barrier Models on Hydrogel Microfluidic Platforms, CS Appl. Mater. Interfaces 2021, 13, 12, 13920–13933 [DOI] 

U17– Jiménez-Jiménez S., Amariei G., Boltes K., García M.A., Marina M.L. Enantiomeric separation of panthenol by Capillary Electrophoresis. Analysis of commercial formulations and toxicity evaluation on non-target organisms. Journal of Chromatography A 1639 (2021) 461919. [DOI]

U16– Fernández-Calderón, M. C., Navarro-Pérez, M. L., Blanco-Roca, M. T., Gómez-Navia, C., Pérez-Giraldo, C., and Vadillo-Rodríguez, V. (2020). Chemical Profile and Antibacterial Activity of a Novel Spanish Propolis with New Polyphenols also Found in Olive Oil and High Amounts of Flavonoids. Molecules 25, 3318. [DOI]

U16– Vadillo-Rodríguez V, Cavagnola MA, Pérez-Giraldo, Fernández-Calderón MC. (2021) A physico-chemical study of the interaction of ethanolic extracts of propolis with bacterial cells. Colloids Surf B Biointerfaces 200, 111571. [DOI]