In vivo ADME and biodistribution assays
Animal Facility:
The VHIR’s Animal Facility includes areas for rodents, rabbits, pigs, minipigs and sheeps. In the case of rodents the facility includes:
– Standard clean area and passive quarantine with an area of 136 m2 with
-10 holding rooms for 225 rats and 11,200 mice
-1 passive quarantine and isolation room with modern microisolators and capacity for 560 mice
-6 handling areas for carrying out experimental and surgical procedures with supplies of gases and inhalable anesthesia as well as surgical microscopes
– A Barrier area with 65 m2 for housing and handling of specific pathogen free (SPF) animals, including immunodeficient mice
-The Molecular Imaging Platform Room, where the molecular imaging equipment is located