Planing, execution and interpretation of in vivo assays requirestime and expertise. At this unit, we give consultancy serviceson preclinical model design, support and advice for research projects, including selection and use of the appropriate imaging system and evaluation and interpretation of the data obtained.
The unit/platform is specialized in oncology and lysosomal storages diseases, and several animal models are available for this type of diseases.
However, we are experienced in developing new efficacy models for testing novel nanomaterials, carriers and therapeutica compounds. Please contact us to see how we can help you in your research Project.
Potential target toxicity of new nanomaterials and drug delivery systems has to be carefully evaluated to support further clinical assays. At U20 we can design, perform and evaluate all type of toxicological studies, including those toxicity analyses performed along with efficacy studiestomore specifically designed long-term or short-term toxicity assays.
Specifically, we provide full services of anatomical pathology, from sample preparation, inclusion, section and staining to anatomopathological evaluation.
JUMISC Animal Housing Unit provides services to companies and research groups in multiple preclinical trials. This unit develops designs and performs preclinical validation on demand. It counts with professionals qualified to design, monitor and validate any type of biomedical study. An important feature of this unit is the possibility to house, maintain and supervise large animals for preclinical validation. This service also counts with a dilated experience in the handling and care of minipigs and what its use in preclinical studies implies.
It has a floor net area of 2.865 m2. It is equipped with spacious rooms to house experimentation animals depending on its specie characteristics (age, sex, weight, breed) and the research projects they are assigned to. Among the equipment and facilities are: rooms for the maintenance of large animals, rooms for the maintenance of small ruminants, rooms for the maintenance of birds, barrier-zone for the maintenance of rodents in SPF conditions, an operating room integrated within the barrier area, multipurpose rooms for the maintenance of rodents and lagomorphs, a room for the reception and handling of the animals, quarantine rooms for pre-experimental processes, a room for small procedures and cures and rooms for the preparation of large animals prior to the surgical area.
Among the services that the Unit develops, we highlight the following:
Customer benefits
All rooms and facilities included in the unit are certified with ISO-9001 and Good Laboratory Practices (GLP), strict quality standards that allow the production of highly accurate results.
In this way, preclinical, security and efficacy studies in animal models can be performed in compliance with the strict guidelines of the regulation agencies, ensuring reliability and traceability of all tests and results performed in its different services.
In addition, this team has been certified by the Spanish Agency of Drugs and Health Products (AEMPS) for studies of “Dosification of problem substances and non-clinical samples”, “Biocompatibility studies of health products”, “In vivo toxicity”, “Tolerance” and “Pharmacodynamics”. All these certifications allow to carry out studies to verify the efficacy, security and biocompatibility of nanotechnological development.
Target customer
The offered services can be of interest to a large number of companies, including the following:
Pharmaceutical and biotechnological companies: Companies that carry out preclinical and clinical studies for the development of drugs, therapies and biotechnological products and require animals to test the efficacy and security of their products.
Academic Researchers: Professors, researchers and students from academic institutions who need access to animals to conduct scientific research in areas like biology, medicine, behaviour, etc.
Medical Institutions: Hospitals, clinics and medical research centres that conduct studies to understand human diseases and develop medical treatments, including preclinical trials on animals.
Medical devices companies: Medical devices manufacturers who need to test the security and efficacy of their products on animals before commercialization.
Regulatory agencies: Government agencies in charge of regulating and monitoring security and efficacy of medical and pharmaceutical products, which may require data from animal studies to support products approval.
Food and agriculture companies: Companies that develop food and agricultural techniques may need to conduct animal studies to evaluate food security, the effects of additives, efficacy in agricultural products, etc.
Additional information
Selected publications:
