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Preclinical validation bioimaging - Equipment

Preclinical validation bioimaging

U25-E06. AVIII 600 MH z

AVIII 600 MH z (14T) spectrometer for high-resolution spectroscopy studies. It is equipped with a Triple Broad Band Inverse (TBI) detection-type probe which makes it suitable for proteomic and metabolomic studies, allowing the analysis of complex mixtures of very different origins (urine, plasma, serum, extracts, biopsies, etc).

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U25-E07. BioSpec 70/30 300 MH z

BioSpec 70/30 300 MH z (7T) spectrometer, suitable for in vivo applications, both spectroscopy and magnetic resonance imaging and microimaging applications. It is sui table for working with small animals, especially rats and mice, although in vitro analyses can also be carried out.

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U25-E08. Focused Microwave Fixation System

Focused Microwave Fixation System, to carry out the immediate sacrifice of small animals (rats, mice), preventing changes occurring in the metabolic pattern of the tissue due to post-mortem metabolism.

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U25-E09. Hypersense sample polarizer

Hypersense sample polarizer, to increase the sensitivity in in vitro and in vivo applications of the AV600 and BioSpec spectrometers. This method not only facilitates the detection of the hyperpolarized substrate in vivo, but also the rapid imaging of cellular metabolism

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U24-E01. Fluoroscopy

  • Cardiac Electrophysiology Laboratory: radiofrecuency ablation system and multicanal poligraph.
  • Fluoroscopy: BV PULSERA Philips Medical Systems
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U24-E02. Digital subtraction angiography system

  • Digital Subtraction Angiography (DSA) (PHILIPS BV- Pulsera Philips Medical System, Netherlands).
  • Digital Subtraction Angiography with flat panel detector (DSA) (PHILIPS Veradius Unity
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U24-E03. Ultrasound scanner

  • Ultrasound scanner (Panther Ultrasound Scanner Type 2002, B&K MEDICAL, Inc. DENMARK.
  • Ultrasound scanner (HDI5000. Philips Medical Systems, Netherlands).
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U24-E04. Computed Tomography (CT) scanner

Computed Tomography (CT), Philips BRILLIANCE CT-6. The CT system includes 24 solid-state detectors that enable the acquisition of 6 simultaneous slices per 360º rotation, with a minimal slice thickness (0.6 mm) at an imaging time of 0.75 seconds per 360º for a full body scan.

These features make a high working speed possible with excellent image quality. The images can be processed in either basic or advanced mode from a workstation with the following software: Angio-CT, CINE mode, dynamic focal point reconstruction, multiplanar reconstruction (linear, curvilinear, etc), 3D multi tissue reconstruction (MIP, VR…), small volumes 3D analysis, and measurement tools for quantification (Q-CTA).

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U24-E05. 1.5T Magnetic Resonance Imaging (MRI) system

Magnetic Resonance Imaging (MRI), Philips- INTERA 1.5T. The MRI equipment (Philips Intera 1.5T) enables the acquisition –using non-invasive techniques- of high definition images of any body organ at different planes, focusing on large animals as experimental models.

The availability of high precision images during research activities enables the researcher to choose correct clinical treatment. This equipment is also used in the follow up of some R&D + innovation lines; during the post operative period of experimental subjects, i.e. in activities such as cellular therapy to measure the therapeutic effect or to evaluate implanted biomaterials.

Thus, this MRI system provides a reliable diagnosis and follow up of certain diseases, allowing the evaluation of state-of-the-art health technologies and their benefits and helping to establish their clinical indications.

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U21-E01. Experimental operating rooms for small and large animal

Experimental operating rooms for small and large animal (inhalation anesthesia workstation, infusion pumps, electrocoagulation systems, laparoscopic surgery systems, endoscopic surgery, microsurgery, interventional and endoluminal surgery, orthopedics, etc.)

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