News U27

4 Units of NANBIOSIS hosted in three Universities among the 200 best in the world in science.

The University of Zaragoza is one of the 200 best universities in the world in science research, according to the latest Shanghai ranking of 2016 in a specific analysis by macro areas.

In order to elaborate this ranking by macroareas indicators such as the number of students and professors who have obtained the Nobel prize or Fields medal, the number of researchers highly cited in the scientific literature, the number of scientific articles indexed in the Science Citation Index and the Percentage of articles published in the most cited 20% scientific journals are used.

Only six Spanish universities are among the 200 best in the world in the field of science, such as the Autonomous University of Madrid, University of Barcelona, University of Santiago de Compostela, Polytechnic University of Valencia, University of Valencia and Zaragoza.

The list of the world’s top 200 universities in science is headed by American universities in Berkeley (California), Stanford, Princeton, Harvard, the Massachusetts Institute of Technology and California, which rank the top six. In the seventh one appears the first European university, Cambridge, followed by the one of Tokyo, Technological Institute of Switzerland and the University of Los Angeles.

NANBIOSIS contributes to this success through the elite researchers that coordinate three of its Units located in the University of Zaragoza: Unit 9 that offers services for sciences research as Synthesis of Nanoparticles biomedicine, micronanotechnology or microfluidics biomedicine, Unit 13 with services as tissue and biomaterial characterization or mechanical tests of tissues and Unit 27 which offers services for sciences research on biomedical computer simulation, modelling of biomedical systems or large simulation multicore and multiserver, among other aspects.

In addition, the Polytechnic University of Valencia and the University of Valencia provides the scientific management and part of the equipment to Unit 26 of NANBIOSIS that offers services for research as molecular imaging metabolomics by NMR or metabolic profiling of biofluids by NMR

Three Universities among the 200 best in the world in science, hosting 4 Units of NANBIOSIS.

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Final Report of European project ITECH accepted by the Commission.

ITECH (Roadmap for Research and Innovation in Health Technologies) is a project of the 7th Framework Programme for research, technological development and dissemination in order to define a strategic plan on Health Technologies to contribute to the Common Strategic Framework for EU Horizon 2020 Research and Innovation.

Pablo Laguna, Scientific Director of Unit 27 of NANBIOSIS has participated in ITECH Committee since the inaugural meeting and kick-off of the project in September 2013. Since then, ITECH has focused on research and innovation in health technologies, medical devices and eHealth applications, it has identified barriers for ideas reaching the market and has proposed some recommendations to overcome them.

For more information:

ITECH final results
A synthesis of the ITECH Project
The final report of the project

Final Report of European project ITECH accepted by the Commission.

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Multi-scale physiology-driven computational tools to assist cardiac disfunctions

Researchers from the unit 27 of NANBIOSIS are developing a Multi scale physiology-driven computational tools to assist cardiac dysfunctions. They have been granted a project of the R+D+I 2016 call of Spanish National Program of “INVESTIGACIÓN, DESARROLLO E INNOVACIÓN ORIENTADA A LOS RETOS DE LA SOCIEDAD”. The project DPI2016-75458-R entitled MULTI-SCALE PHYSIOLOGY-DRIVEN COMPUTATIONAL TOOLS TO ASSIST IN THE ASSESSMENT AND MANAGEMENT OF CARDIAC DYSFUNCTIONS is led by Juan Pablo Martinez and Esther Pueyo, of the BSICDoS-i3A and CIBER-BBN group.

Both, multi-scale computational modelling, necessary to reproduce the experimental and clinical observations and the signal analysis (cellular, intracardiac and surface), shall be developed using the computing platform, Unit 27 of NANBIOSIS.

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Pablo Laguna and Jordi Aguilo, Scientific Directors of the Units 27 and 8 of NANBIOSIS participate in the European program Remote Assessment of Disease and Relapse in Central Nervous System Disorders (RADAR-CNS)

RADAR-CNS is an important European research program supported by the Innovative Medicines Initiative (IMI) focused to develop new ways of monitoring patients affected by major depression, epilepsy and multiple sclerosis, with the use of wearable technology and smart mobile phones.

This program brings together experts from various disciplines in clinical research, engineering, computer and data analysis, as well as health services. RADAR-CN aims to improve symptoms and quality of life of patients and treatment of these and other chronic diseases. This program is jointly led by King’s College London and the pharmaceutical company Janssen and is funded by the Innovative Medicines Initiative (a public-private agreement EFPIA and the European Union). RADAR-CNS involves 24 organizations in Europe and US, including CIBER through its thematic areas of Mental Health (CIBERSAM) and Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN)

“In recent years, the quality and quantity of data that can be collected with the wearable technology and smart phones has increased a lot. The information generated with this large amount of data will help to improve clinical care by providing greater detail of the patient’s condition and prognosis of its evolution. Moreover, it will be possible to detect whether a patient is beginning to have problems before there is clinical evidence of it” says Dr. Jordi Aguilo, scientific coordinator of the Unit 8 of NANBIOSIS.

This huge generate data sets, suitable to be stored and treated so to retrieve the relevant information hidden in the data, frequently require computing systems and information systems of high performance. The Unit 27 of NANBIOSIS will be the platform in which this analysis will be performed.

Pablo Laguna and Jordi Aguilo, Scientific Directors of the Units 27 and 8 of NANBIOSIS participate in the European program Remote Assessment

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Last Friday, 27th May, the "Instituto de Investigación en Ingeniería de Aragón" held the "V Jornada de Jóvenes Investigadores" where phD students presented their works related to different areas: Industrial Technologies, Biomedical Engineering, Processes and Recycling and Information and Communications Technology.

Last Friday, 27th May, the “Instituto de Investigación en Ingeniería de Aragón” held the “V Jornada de Jóvenes Investigadores” where phD students presented their works related to different areas: Industrial Technologies, Biomedical Engineering, Processes and Recycling and Information and Communications Technology.

David Adolfo Sampedro Puente, member of the BSICoS, group coordinator of Unit 27 of NANBIOSIS, presented the work entitled “Unscented Kalman Filter for Unobservable Parameter Estimation in Heart Cell Signals”, supervised by Jesús Fernández Bes and Esther Pueyo Paules. This work shows a methodology to estimate unobservable parameters, such as the number of the different ion channel typologies located in the cardiomyocyte membrane, from action potential (AP) signals. This methodology was validated using synthetic AP signals simulated by stochastic computational cell models. In future, this methodology will be used to real signals, recorded in human cardiomyocytes, to help to the study of the AP temporal variability characterization.

Nanbiosis U27-Unscented Kalman Filter for Unobservable Parameter Estimation in Heart Cell Signals by David Sampedro

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Esther Pueyo nominated for the awards Aragonese of the Year 2015 for her research on aging heart, carried through the computational capabilities of Unit 27 of NANBIOSIS

Esther Pueyo, researcher at the group of CIBER-BBN, BSICoS, which coordinates Unit 27 of NANBIOSIS, has been nominated for awards Aragonese of the Year in the category of science and research. Esther develops a project considered of reference by European Union that studies aging heart through mathematical and computational tools combined with experimental and clinical work aimed at proposing new markers of risk for arrhythmias.

The Newspaper El Periódico de Aragon calls for the twenty second consecutive year Aragonese of the Year, a competition that recognizes the personal and professional Aragonese citizens and groups who develop their work in different fields, always with social significance merits.

The Aragonese of the Year contest is divided into five categories, with four nominations each. One that gets the most votes will rise to the Aragonese Year award in the cathegories: Company, Sports, Human Values, Science and Research and Culture

Esther Pueyo (U27 Nanbiosis) nominated for Aragonese of the Year 2015 for her research on aging heart

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Government of Aragón, Spain, paid tribute to the seven scientists who have a grant of European excellence and develop their projects at the University of Zaragoza: Jesús Santamaría, Diego Gutierrez, Igor Irastorza, Esther Pueyo, Manuel Arruebo, José Manuel García Aznar and Jesús Martínez de la Fuente.

President of the Government of Aragon, Javier Lambán, has personally expressed his gratitude and appreciation for the work of seven researchers from the University of Zaragoza who have been granted with projects of excellence funded by the European Research Council.

Jesús Santamaría, Scientific Director of Unit 9 of NANBIOSIS, with an Advanced Grant funded with 1.85 million euro, is working on a project to develop a microreactor that enables the industry to save energy and raw materials.

Esther Pueyo, member of the research group BSICoS of CIBER-BBN, which coordinates Unit 27 of NANBIOSIS, has a Starting Grant of 1.5 million and is studying the aging of the heart to propose new markers of risk for arrhythmias in the aging population.

Manuel Arruebo member of the research group Nanostructured films and particles of CIBER-BBN, which coordinates Unit 9 of NANBIOSIS, with a Grant Consolidator 1.5 million for the project Nanohedonism, develops injectable nanoparticles created with microfluidic reactors for the controlled and remote delivery of drugs in the treatment of chronic pain.

Nanbiosis_U27_U9_Three researchers of NANBIOSIS among the seven Aragonese scientists granted with an ERC.

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Pablo Laguna, Scientific Director of the Unit 27 of NANBIOSIS, presents in the Neocom Days the research lines of the group Biomedical Signal Interpretation & Computational Simulation (BSICoS) of CIBER-BBN and I3A of University of Zaragoza.

NEOCOM DAYS are organized by the Alumni Association of Telecommunications at the University of Zaragoza (AATUZ) in order to gather once a year companies, students and teachers to pool developments in the sector of new technologies in the field of Communications.

Nanbiosis U27_Biomedical Signal Interpretation & Computational Simulation (BSICoS)_Zaragoza

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On March 2, 2016 Esther Pueyo, Tenured Professor at the University of Zaragoza and member of the research group BSICoS of CIBER-BBN, presented the research lines of this group, that coordinates Unit 27 of NANBIOSIS, and described the ERC MODELAGE project, which was awarded with a 'Starting Grant' of the European Union funded with 1.5 million euros.

The project progresses in the characterization of human heart aging and the prevention of cardiac arrhythmias. Juan Pablo Martínez, coordinator of the BSICoS group, introduced and moderated the talk, which is incardinated in the series of seminars “Ateneo de la Escuela de Ingeniería y Arquitectura”, where ideas on science, technology, scientific thinking, social and human sciences, etc, are presented and discussed.

Current technology allows addressing multi-factorial and multi-scale research of cardiac electrophysiological behavior to improve arrhythmic risk stratification in aged hearts, both on a population basis but also on an individual basis. Esther Pueyo presented the methodologies proposed in the MODELAGE project for this purpose, which integrate in silico modeling with in vitro cell and tissue analysis and in vivo assessment of electrocardiographic recordings. All these investigations will be made possible thanks to the computational capabilities of Unit 27 High Performance Computing of NANBIOSIS.

Nanbiosis_U27-Esther Pueyo presents- Engineering at the service of health-study of human heart aging

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