News U26

Research Excellence Award by the Spanish Royal Society of Chemistry to Ramón Martínez, Scientific Director of Unit 26 of NANBIOSIS

The Governing Board of the Spanish Royal Society of Chemistry (SRSQ) has agreed to grant its Research Excellence Award 2016 to Dr. Ramón Martínez Máñez, Scientific Director of Unit 26 of NANBIOSIS and Scientific Director of CIBER-BBN, in recognition of the quality and innovation of its research in the design of chrome-fluorogenic detection probes and the development of new delivery systems and their impact on biomedical applications.

Martinez Máñez is co-authored of more than 330 scientific publications in international journals. His scientific work has been cited on over 13,000 occasions. It is among the 15 most cited authors in the area of Chemistry in Spain in recent years and currently has an index h of 56. He is currently Director of the Interuniversity Research Institute for Molecular Recognition and Technological Development (IDM) at the Politecnic University of Valencia. He has been coordinator of Project Evaluation Technology Area at the Generalitat Valenciana and member of the Committee of Experts for the Selection of Projects of the National Plan in 2010 and 2014 in the Thematic Area of Materials. Currently, he is also coordinator of the PhD Program in Chemistry and a member of the Steering Committee of the Doctoral School of the UPV, Co-chairman of the magazine ChemistryOpen published by Wiley and member of the International Advisory Board of the Chemistry journal Asian. Chem. J. and ChemPlusChem, published by Wiley

Nanbiosis U26-Research Excellence Award by the Spanish Royal Society of Chemistry to Ramón Martínez, Scientific Director of Unit 26 of NANBIOSIS

• Read More

Ramon Martinez Mañez, Scientific Director of Unit 26 of NANBIOSIS, has participated in the development of new nanodevices that allow the controlled release of drugs, namely doxorubicin, for therapies against breast cancer.

So far, the work has focused on cellular assays, with positive results, that could open new ways to improve the effectiveness of some drugs used in the treatment of breast cancer.

The main novelty of these nanodevices is that the molecule covering the nanodevice not only controls when the transported drugs are released, but also controls where they are released to direct them to cells expressing TLR3, a protein of the innate immune system overexpressed in some cell lines of breast cancer. Through this protein it is also launched a death signal that ends with the tumor cell.

Their study was published last January in Chemistry-A European Journal:

Ultimo A, Giménez C, Bartovsky P, Aznar E, Sancenón F, Marcos MD, Amorós P, Bernardo AR, Martínez-Máñez R, Jiménez-Lara AM, Murguía JR.Targeting Innate Immunity with dsRNA-Conjugated Mesoporous Silica Nanoparticles Promotes Antitumor Effects on Breast Cancer Cells. Chemistry. Chemistry – A European Journal. DOI: 10.1002/chem.201504629

Nanbiosis_U26_New nanodevices to improve therapy for breast cancer

• Read More

You are here : Home / News U26 (Page 6)

Research Excellence Award by the Spanish Royal Society of Chemistry to Ramón Martínez, Scientific Director of Unit 26 of NANBIOSIS

Ramon Martinez Mañez, Scientific Director of Unit 26 of NANBIOSIS, has participated in the development of new nanodevices that allow the controlled release of drugs, namely doxorubicin, for therapies against breast cancer.