JUMISC

II COURSE FOR THE PERFORMANCE OF FUNCTIONS A, B AND C IN RODENTS, LAGOMORPHES, CARNIVORES, PIGS AND SMALL RUMIANTS

JUMISC has organised the II Course for the performance of functions A, B and C in rodents, lagomorphes, carnivores, pigs and small rumiants which wil take place at JUMISC from 3 February to 20 March co-Directed by D. LUIS DÁVILA GÓMEZ, Scientific Director of NANBIOSIS U22. Animal housing and DR. FRANCISCO MIGUEL SÁNCHEZ MARGALLO (Deputy Scientific Director of NANBIOSIS)

The total duration of the course is 100 hours (58 theory and 42 practice)

This course has as specific objectives to provide information and expand existing knowledge in the following aspects:
-Specific legislation regarding animal experimentation .
-Ethical considerations and the principles of replacement, reduction and refinement.
-Biology, housing, handling and care of experimental animals.
-Occupational health and safety.
-Recognition of the state of health and disease of experimental animals.
-Implications of the microbiological status of animals in the experimental process.
-Anesthesia, analgesia and basic principles of surgery.
-Realization of specific procedures with experimental animals and their practical development.
-Bloodless methods of euthanasia of animals.

Programm and inscriptions here

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BASIC COURSE FOR UROLOGIS: INTRACORPOREAL SUTURING

CCMIJU has organised the II Urological Laparoscopy Course: Suture Management and Intracorporeal Knotting which wil take place at JUMISC from 3 to 5 February under the Direction of Álvaro Serrano Pascual (Urology Service Specialist at the San Carlos Clinical Hospital, Madrid) and Francisco Miguel Sánchez Margallo (Deputy Scientific Director of NANBIOSIS)

It is a basic course of Laparoscopic Urology where the techniques of Laparoscopic Radical and Partial Nephrectomy will be carried out. The objective of this course is for specialists in Urology to improve their skills in suture management and intracorporeal knotting.

Programm and inscriptions here

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NANBIOSIS internal dissemination day

NANBIOSIS has celebrated today the second edition of NANBIOSIS internal dissemination day, at the ICMAB-CSIC, Barcelona.

The Day has been focuss on the staff that deals with the day-to-day work of the units, especially technical staff. The event was attended by technicians and coordinators of the units of Catalonia and Aragon (almost 30 face-to-face assistants) and has been followed through the streaming broadcast by the other units.

The day has been presented by the NANBIOSIS Scientific Director Jaume Veciana and the Nerea Argárate Coordinator, followed by a round of presentations by the attendees and their work in the different NANBIOSIS units.

The first part has focused on the Cutting Edge Biomedical Solutions as integral solutions to the problems that arise in biomedical research integrating the expertise of several units presented by Nerea Argarate, as well as several presentations from the units of the Minima invasion Surgery Center Jesus Usón de Cáceres CCMIJU by Javier García, Jorge Bote and Verónica Crisóstomo focused on potential internal collaborations, synergies and complementarities in NANBIOSIS between the CIBER, CCMIJU and Bionand units.

The second part dealt with the implementation of quality systems, the NANBIOSIS coordinator has presented the NANBIOSIS Quality Plan and Arnau Jaumandreu (NANBIOSIS Unit 6 Technician) has made a good summary of the steps to follow in the implementation of a quality system with recommendations from its experience in the process followed by unit 6, all followed by a debate.

In the last part Anna May Masnou (Head of Communication and Dissemination of ICMAB-CSIC) has spoken about the use of the NANBIOSIS brand and communication channels, the dissemination of science and its returns. The day has ended with a space for debate.

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I ONLINE Course on Introduction to Quality Management in Laboratories in the Biosanitary Field

The Jesús Usón Minimally Invasive Surgery Center (JUMISC), organizes the 1st ONLINE Course on Introduction to Quality Management in Laboratories in the Biosanitary Field.

The course will count with the expertise Beatriz Moreno Lobato, Scientific Director of NANBIOSIS Unit 19 CLINICAL TEST LAB, among others.

The Course is directed to middle-level technicians: Auxiliary Care of Nursing and Pharmacy and Parapharmacy and also to higher degree technicians: Pathological and Cytodiagnostic Anatomy, Oral Hygiene, Image for Diagnosis and Nuclear Medicine, Clinical and Biomedical Laboratory, Dental Prosthetics, Dietary

The course has a capacity for forty attendees and registration is now open here:

The course program consists of:
Thematic Unit 1: Quality Management Systems (7.5h) (15h student dedication)

Historical justification and principles of quality management (1,5h) (J Sánchez)
Quality Assurance Systems (J Sánchez)
ISO 9001 (1,5h) (J Sánchez)
ISO 17025 Standard (1,5h) (J Sánchez)
BPL regulations (1,5h) (J Fco Guillén)
Quality Philosophy. New strategies (1,5h) (J Sánchez)

Thematic Unit 2: Quality in the field of the laboratory (8.5h) (17h student dedication)

Generalities and Management in a Clinical Analysis Laboratory (2h) (B Moreno)
Safety standards in laboratories (2h) (J Boat)
Quality in other laboratories in the biomedical field (4,5h) (N Hernández / J García / N Picado)

Thematic Unit 3: Analytical Quality (4h) (8h student dedication)

Definition of analytical quality. General aspects (B Moreno)
Analytical tests (B Moreno)
Management and conservation of samples. Analytical Interferences (B Moreno)
Validation of analytical methods (B Moreno)
Calibration and equipment management. Quality and PNT manuals (J Fco Guillén / B Moreno)

Thematic Unit 4: Introduction to GLP (4h) (8h student dedication)

Regulation and relationship with other standards (J Fco Guillén)
ISO 13485 and other related standards (J Fco Guillén)
Documentation and Quality Assurance (J Fco Guillén)
BPL applications (B Moreno)

Final exam and Satisfaction Survey (2h)

Detalle de Curso

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III Conference on the Disclosure of Biomedical and Experimental Sciences

The III Conference for the Disclosure of Biomedical and Experimental Sciences will take place at the Center for Minimally Invasive Surgery Jesús Usón of Cáceres, on December 5, 2019. It will be attended by Francisco Miguel Sanchez Margallo, Deputy Scientific Director of NANBIOSIS and Beatriz Moreno Lobato, Scientific Director of Unit 19 of NANBIOSIS

FREE ACTIVITY – Requires prior registration until full capacity is reached

Pre- registration: https://www.ccmijesususon.com/formacion/preinscripcion/1173/

Program:

Detalle de Curso

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CCMIJU: Online Course on INTRODUCTION TO RESEARCH AND LABORATORY TECHNIQUES IN BIOCIENCES

During de dates Nov. 18 -30, 2019 will take place de course on line on Introduction to Research and Laboratory Techniques in Biociences, under the direction of NANBIOSIS U14 Cell Therapy Unit led by Javier García Casado Scientific Director of the Unit and Francisco M. Sánchez Margallo Scientific Director of CCMIJU and Deputy Scientific Director of NANBIOSIS.

For further information: Online Course on INTRODUCTION TO RESEARCH AND LABORATORY TECHNIQUES IN BIOCIENCES

Matriculación online

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“Minimal invasion, maximum innovation”

“Minimal invasion, maximum innovation” is a repot by Spanish TV about the Minimal Invasion Surgery Center, Jesús Usón, partner of NANBIOSIS.

“The unique capabilities of the Center from its animal farm to its surgical infrastructure allow the evaluation and validation of new technology such as medical devices, new biomaterials, new pharmacological therapies, before being used in human patients” explains Francisco Miguel Sanchez Margallo, Sciencitific Director of the Center and Deputy Scientific Director of NANBIOSIS- ICTS.

Verónica Crisóstomo, Scientific Director of NANBIOSIS Unit 24 of Medical imaging explains a current project that studies how to reduce the damage caused by a heart attack with stem cell-based treatment

The report can be seen heer:

http://www.rtve.es/m/alacarta/videos/lab24/lab24-reportaje-minima-invasion-maxima-innovacion/5425735/

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Scientific breakthrough against the problems of advanced age in fertility.

Researchers of CCMIJU. led by Javier G. Casado, Scientific Director of NANBIOSIS U14 Cell Therapy, are coauthors of the article “Extracellular vesicles derived from endometrial human mesenchymal stem cells enhance embryo yield and quality in an aged murine model” published by. Biology of Reproduction,

The study of the beneficial effect of endometrial stem cell exosomes on embryonic quality has been developed in NANBIOSIS U14 and in collaboration with U22 and U23

Advanced age is a risk factor undermining women’s fertility. Hence, the optimization of assisted reproduction techniques is an interdisciplinary challenge that requires the improvement of in vitro culture systems. Here, we hypothesize that supplementation of embryo culture medium with extracellular vesicles from endometrial-derived mesenchymal stem cells (EV-endMSCs) may have a positive impact on the embryo competence of aged oocytes. In this work, 24 weeks old B6D2 female mice were used as egg donors and in vitro fertilization assays were performed using males from the same strain (8–12 weeks); the presumptive zygotes were incubated in the presence of 0, 10, 20, 40, or 80 μg/ml of EV-endMSCs. The results from the proteomic analysis of EV-endMSCs.

In summary, the supplementation of embryo culture medium with extracellular vesicles from endometrialderived mesenchymal stem cells increases the quality of aged embryos.

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Laparoscopic surgery in the uterus retrieval procedure during uterine transplantation

Researchers of NANBIOSIS units at JUMISC have recently published the results of an study that highlights the promising application of laparoscopy for graft procurement surgery in uterine transplantation from living donors for absolute uterine infertility treatment. Laparoscopy seems to be a safe, time saving, useful and technically feasible surgical procedure for uterus extraction, with the additional benefits of minimally invasive surgery. It was also demonstrated that after a successful uterine transplant, pregnancy can be achieved by combining laparoscopy for uterine retrieval and microsurgery for vascular anastomosis. With the increasing success rate of human uterus transplantation trials from living donors, it is very probable that laparoscopic graft extraction will soon become a reality in the transplantation field. However, uterus transplantation will remain as a clinical experimental procedure until sufficient experience is achieved.

The resarch has been executed by using the Unique Scientific and Technical Infrastructure (ICTS) “NANBIOSIS.”

Article of reference:

Francisco Miguel Sánchez-Margallo, Belén Moreno-Naranjo, María del Mar Pérez-López, Elena Abellán, José Antonio Domínguez-Arroyo, José Mijares & Ignacio Santiago Álvarez. Laparoscopic uterine graft procurement and surgical autotransplantation in ovine model Scientific Reports 9, Article number: 8095 (2019)

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DEVELOPING A SENSOR FRAMEWORK FOR MINIMALLY INVASIVE SURGERY

Francisco Miguel Sánchez Margallo, Scientific Director of the Minimally Invasive Surgery Center ‘Jesús Usón’ and Deputy Director of NANBIOSIS, leads, together with Thomas Malone, of the Massachusetts Institute of Technology (MIT), in the United States, the project selected by the MIT program -Spain ‘La Caixa’ Foundation Seed Fund “Developint a sensor framework for minimally invasive surgery”.

The project seeks to develop a system of sensors to analyze health parameters of the surgeon, such as his physiological and ergonomic state, as well as the interaction between this and the patient during surgery. It is a disruptive research project on sensors to improve the health of the surgeon and the quality of surgery. NANBIOSIS units at JUMISC will play an important role in the development of the project.

This program was born with the aim of promoting the interrelation between Spanish research groups of excellence and those of MIT. The initiative aims to generate synergies and facilitate collaboration in international projects with a pioneering entity at the international level such as MIT.

The collaboration with MIT brings great value to Spanish research, since it is one of the best international research institutions. Among the professors about 80 Nobel prizes are counted, and its students have promoted more than 30,000 companies.

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