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High perfomance computing - Services

High perfomance computing – Services

Ibima: At the Forefront of Research with a Unique New Infrastructure in Andalusia

Ibima-plataforma BIONAND has inaugurated an innovative radioactive facility that will advance new diagnosis and treatments through the development of radiopharmaceuticals.

Malaga, December 2024. Málaga reaffirms its position as a leader in scientific innovation with the opening of a new radioactive facility, unique in Andalusia. This cutting-edge space, owned by the University of Málaga, is located within the Málaga Biomedical Research Institute and Nanomedicine Platform (Ibima BIONAND Platform), which is integrated into our Unit 28. It will facilitate the development of new drugs and therapies for treating various diseases, including cancer.

Moreover, due to its exceptional features and potential, this new facility has been included in the Ministry of Science, Innovation, and Universities’ map of Singular Scientific and Technical Infrastructures (ICTS). This designation highlights spaces distinguished for their excellence in equipment and services.

As noted by the Ministry, ICTS are “unique or exceptional in their kind.” Their high investment, maintenance, and operational costs, combined with their strategic importance, justify their availability to the entire national and international scientific community. NANBIOSIS also has this type of designation.

“Today, we inaugurate something very specific, very powerful, and very innovative.”

Dr. Francisco J. Tinahones

A Great Responsibility

“Today, we inaugurate something very specific, very powerful, and very innovative,” stated Francisco J. Tinahones, Scientific Director of Ibima, emphasizing the “great responsibility” that comes with being designated as an ICTS. “We have a task, and we all must undertake it to ensure that this structure is utilized to its full potential, enabling researchers from Málaga and beyond to use it and reap its benefits,” he insisted.

Visit to the radioactive facility of IBIMA-plataforma BIONAND. / Photo: Alex Zea

This new radioactive facility, approved on October 9 by the Nuclear Safety Council, has been integrated into the NanoImaging Unit of NANBIOSIS, and forms a cornertone within our own network of country-wide Units. “It belongs to a larger ICTS; it’s the third pillar,” clarified María Luisa García, Scientific Director of the ICTS node, explaining that its uniqueness is granted by the facility’s design and equipment.

“There is no other center like this in Andalusia; it’s the only one.”

Dr. Mónica Feijoo Cuaresma

A Gateway to New Therapies

“There is no other center like this in Andalusia; it’s the only one,” pointed out Mónica Feijoo Cuaresma, coordinator and supervisor of this new radioactive facility. She highlighted that this space will enable research contributing to the development of new radiopharmaceuticals for treating various diseases, such as cancer, neurodegenerative, cardiac, inflammatory diseases, obesity, allergies, or diabetes.

Visit to the radioactive facility of IBIMA-plataforma BIONAND. / Photo: Alex Zea

“There are different rooms and specialized equipment designed for the development of radiopharmaceuticals to monitor diseases, evaluate new early diagnostics, and create new therapies,” explained Dr. Feijoo. These radiopharmaceuticals, for instance, allow researchers to generate tumors, track their evolution, test new therapies, and determine their effectiveness. “A radiopharmaceutical is a drug to which you attach a radioactive isotope for visualization,” García added, summarizing that “radioactivity allows you to visualize and treat; it enables both diagnosis and therapy.”

“We work with animal models, specifically rats and mice.”

Dr. Mónica Feijoo Cuaresma

The facility, which required a €1.3 million investment, features a Radiopharmacy classified as a clean room, providing an environment free from contamination to manufacture new radiopharmaceuticals for preclinical research. “We work with animal models, specifically rats and mice,” noted Feijoo.

Facilities Highlights

The crown jewel of this facility is the multimodal molecular imaging room (PET/SPECT/CT), capable of acquiring images using both PET and SPECT radiopharmaceuticals as well as CT scans. “This trimodal equipment is extremely special because it is used in clinical settings, making it crucial for preclinical development of radiopharmaceuticals with a device that can later be transferred to patient care,” emphasized Feijoo.

Visit to the radioactive facility of IBIMA-plataforma BIONAND. / Photo: Alex Zea

“This trimodal equipment is extremely special because it is used in clinical settings, making it crucial for preclinical development of radiopharmaceuticals with a device that can later be transferred to patient care.”

Dr. Mónica Feijoo Cuaresma

The facility also includes an area dedicated to X-rays, equipped with an irradiator for generating immunodeficient animal models and for therapeutic applications, as well as an optical imaging system for in vivo fluorescence and bioluminescence, alongside 2D X-ray imaging. Completing the infrastructure are a radiochemistry lab and an area for managing radioactive waste in compliance with the Nuclear Safety Council’s regulations.

A Long and Challenging Path

Reaching this milestone has not been easy, as recalled by Juan Teodomiro López, Rector of UMA, during the inauguration ceremony. He expressed being “absolutely delighted” and emphasized that this new facility will enable research of “the highest caliber.”

Inauguration of the radioactive facility of IBIMA-plataforma BIONAND. / Photo: Alex Zea

In a similar vein, Sergio Cañete Hidalgo, Rector’s Delegate for Services Coordination and Inspection, underscored the importance of this facility, describing it as “not only unique in Andalusia but arguably in Spain.” He also praised the highly qualified and specialized team that will allow various research groups, both national and international, to elevate their work to a new level of excellence.

This article was written by Arancha Tejero for La Opinión de Málaga on December 18, 2024. Translated and edited by NANBIOSIS.

What is NANBIOSIS?

The goal of NANBIOSIS is to provide comprehensive and integrated advanced solutions for companies and research institutions in biomedical applications. All of this is done through a single-entry point, involving the design and production of biomaterials, nanomaterials, and their nanoconjugates. This includes their characterization from physical-chemical, functional, toxicological, and biological perspectives (preclinical validation).

Leading scientists

The main value of NANBIOSIS is our highly qualified and experienced academic scientists, working in public institutions, renowned universities and other research institutes.

Custom solutions

Designed for either scientific collaboration or the private industry, we adapt our services to your needs, filling the gaps and paving the way towards the next breakthrough.

Cutting-Edge facilities

Publicly funded, with the most advanced equipment, offering a wide variety of services from synthesis of nanoparticles and medical devices, including up to preclinical trials.

Standards of quality

Our services have standards of quality required in the pharmaceutical, biotech and medtech sectors, from Good Practices to ISO certifications.

In order to access our Cutting-Edge Biomedical Solutions with priority access, enter our Competitive Call here.

NANBIOSIS has worked with pharmaceutical companies of all sizes in the areas of drug delivery, biomaterials and regenerative medicine. Here are a few of them:

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U27-S06. Mass storage

Mass storage

we provide a robust and versatile solution to handle large amounts of data efficiently based on market-leading technology. We have high-performance distributed storage to store experimental data during your work and make it accessible within our infrastructure for all tasks that require it. Our system of triple replication on network guarantees data integrity and availability at all times.

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U27-S05. Massive Parallel Processing

Massive Parallel Processing

Harnessing the power of parallel computing, we tackle large-scale data challenges with efficiency.With a large amount of equipment for calculations and processing on CPU and GPU, we can accelerate the work of months, in conventional equipment, to hours on our infrastructure. As evidenced by the approval of a large number of researchers in the area who have conducted their research on it.

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U27-S01. Remote access to HPC

Remote access to HPC

The HPC service allows remote access to High Performance Computing, Massive Parallel Processing, Mass Storage and different software applications. Designed to meet the demands of projects requiring exceptional computational performance, our service provides users with the flexibility and power to address a wide variety of challenges. It responds to the increasing complexity of simulations carried out by the most advanced research projects.

Customer benefits

The “Remote Access to Infrastructure with Massively Parallel Processing in HPC” service offers our clients distinctive advantages that not only meet their requirements but also add significant value to their Research and Development projects. 

  • Exceptional Performance: We provide our clients with access to cutting-edge HPC infrastructure, ensuring exceptional computational performance. 
  • Flexibility for Various Applications: Our service is generic and highly adaptable, satisfying a wide variety of R&D applications. 
  • Elimination of Geographic Restrictions: By offering secure remote access to our infrastructure, we eliminate geographic limitations.

Essential Scenarios:

  • Cutting-edge Scientific Research: Our service is essential for projects that require significant computational power, such as detailed molecular dynamics simulations, biomedical and biochemical modeling, simulations of all types, etc. 
  • Development of High-Performance Algorithms: our service is crucial for testing and optimizing high-performance algorithms, ensuring efficient execution in production environments. 
  • Complex Data Analysis and Big Data: In projects that involve the analysis of large data sets, from genomic sequencing to artificial intelligence, our service allows for massively parallel processing, improving the speed and accuracy of the analysis.

Target customer

The service is designed to meet the specific needs of diverse user groups, allowing them to take full advantage of massively parallel processing capabilities. 

  • Scientific Researchers and Academics: We provide access to cutting-edge HPC infrastructure, allowing them to perform advanced simulations, complex modeling and data analysis at a scale that goes beyond the capabilities of conventional systems. 
  • High Performance Software Development Teams: Intensive algorithms and high-performance applications, we offer a scalable platform that facilitates extensive testing and optimization to ensure optimal performance. 
  • Biomedical Research Institutions: can leverage our infrastructure for the analysis of large data sets, detailed simulations and complex studies, driving significant advances in the understanding of diseases and the development of therapies. 
  • Artificial Intelligence and Machine Learning teams: can leverage our infrastructure for training complex models and analyzing massive data sets.

Additional information

The HPC service has more than 3260 cores and 5920 parallel processing threads, 26TB of RAM, 264TB NVMe and 400TB HDD of shared storage, all connected by a 100Gbps backbone network. In addition, we currently offer 251,392 CUDA cores, 720GB graphics memory, 1,179.42 peak FP16 TFLOPS, and 828.6 peak FP32 TFLOPS.

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U27-S02. Software installation on demand

Software installation on demand

This Unit offers an exceptional software installation service that is not present in our infrastructure. We study each case to try to find the best solution, as long as it fits the technical characteristics, both hardware and software of the Unit.

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U27-S03. Biomedical signals processing

Biomedical signals processing

In our continued commitment to providing advanced solutions in High-Performance Computing (HPC), we are proud to present our specialized service in “Biomedical Signal Processing”. This service harnesses the power of high-performance computing to facilitate the analysis and interpretation of biomedical signals, offering advanced solutions for a variety of clinical and research scenarios.
The HPC service allows remote access to High Performance Computing, Massive Parallel Processing, Mass Storage and different software applications. It responds to the increasing complexity of simulations carried out by the most advanced research projects.

Customer benefits

The “Biomedical Signal Processing” service offers our clients specific advantages by providing access to our advanced High-Performance Computing (HPC) infrastructure, adding significant value to your Research and Development (R&D) activities. Focusing on the critical scenarios in where our service becomes essential, we highlight the following advantages: 

  • Validation of Theoretical Models: We allow researchers to validate and adjust theoretical organ models through detailed simulations, using computing power to compare theoretical results with experimental data. 
  • Custom Algorithm Development: Researchers and scientists can leverage HPC infrastructure to develop and refine custom signal processing algorithms tailored to their specific research objectives. 
  • Analysis of Large Data Sets: For projects involving the analysis of large data sets of biomedical signals, we offer the processing power necessary to perform detailed evaluations and extract meaningful patterns.

Target customer

Access to our HPC infrastructure is designed to meet the needs of diverse user groups, allowing them to perform specialized calculations and experiments in the field of biomedical signal processing.

  • Researchers and Scientists: We offer biomedical engineering  researchers access to HPC resources to perform advanced simulations, validate theoretical models and explore new perspectives in the diagnosis and treatment of cardiac diseases.
  • Biomedical Algorithm Developers: For those focused on developing and refining specific signal processing algorithms, we provide the necessary infrastructure to implement and evaluate custom algorithms.
  • Healthcare Professionals and Biomedical Engineers: Healthcare professionals and biomedical engineers can use our HPC platform to analyze and process large signal data sets, improving efficiency in the analysis of clinical information and the development of advanced medical technologies.
  • Biomedical Technology Companies: We provide them with the ability to test and validate their products in simulated environments, optimizing the performance and precision of their solutions.

Additional information

The HPC service has more than 3260 cores and 5920 parallel processing threads, 26TB of RAM, 264TB NVMe and 400TB HDD of shared storage, all connected by a 100Gbps backbone network. In addition, we currently offer 251,392 CUDA cores, 720GB graphics memory, 1,179.42 peak FP16 TFLOPS, and 828.6 peak FP32 TFLOPS.

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U27-S04. Modeling of the functional behaviour of tissues and organs

Modeling of the functional behaviour of tissues and organs

In our continued commitment to providing advanced solutions in High-Performance Computing (HPC), we are pleased to introduce our “Modeling the Functional Behavior of Tissues and Organs” service. This service leverages the power of high-performance computing, massively parallel processing, mass storage and different software applications to provide detailed and accurate analysis of the functional dynamics of tissues and organs.

Customer benefits

Our service significantly reduces work times, moving simulation processes from weeks to days. Additionally, it enables the simulation of different scenarios and parameters simultaneously.

  • Precision and Reliability: Our High-Performance Computing (HPC)-based simulations provide an unmatched level of precision and reliability in modeling the behavior of tissues and organs. This ensures reliable results and high-quality data to inform critical research decisions. 
  • Effective Optimization: By addressing the complexities of biological processes, our service facilitates the optimization of intervention strategies. Organizations can make precise adjustments to treatments and procedures, reducing costs and improving the effectiveness of therapeutic approaches. 
  • Risk Reduction in Development: Through virtual simulations of medical scenarios, organizations can identify and mitigate risks before practical implementation. This is essential in Research and Development, where error reduction and continuous improvement are imperative.

Target customer

Our “Modeling of the Functional Behavior of Tissues and Organs” service is designed to meet the specific needs of various stakeholders engaged in Research and Development, offering solutions adapted to the particular demands of the following key audience:

  • Biomedical and Scientific Researchers: providing them with advanced tools to thoroughly understand the functional behavior of tissues and organs. We facilitate detailed analysis of complex data and simulation of relevant scenarios to drive significant advances in scientific knowledge.
  • Pharmaceutical and Biotechnology Companies: making it easier to obtain detailed information on the response of tissues to specific compounds, accelerating the development process and improving success rates in creating effective treatments.
  • Health Professionals and Clinicians: personalized medicine, facilitating the personalization of treatments, allowing health professionals to adapt interventions according to the individual characteristics of patients. This is particularly valuable in optimizing therapeutic protocols and improving clinical outcomes.
  • Academic Research Institutions: essential for academics and students engaged in the exploration and understanding of biological processes.

Additional information

The HPC service has more than 3260 cores and 5920 parallel processing threads, 26TB of RAM, 264TB NVMe and 400TB HDD of shared storage, all connected by a 100Gbps backbone network. In addition, we currently have 251,392 CUDA cores, 720GB graphics memory, 1,179.42 peak FP16 TFLOPS, and 828.6 peak FP32 TFLOPS.

Read More