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U6-E09. Nanosight LM -20 for Nanoparticle Tracking Analysis

Nanosight LM -20 for Nanoparticle Tracking Analysis.

Description: Particle size distribution (from 10 to 1000nm) and particle concentration by real-time visualization of nanoparticles in a liquid

Technical Specifications:

Nanoparticle analysis range: typically 10 nm – 1000 nm, dependent on particle material

Particle type: any

Solvent: any non-corrosive solvent and water. A range of solvent-resistant seals are available.

Sample volume requirements: 0.3 ml

Applications: Particle size distribution and particle concentration by real-time visualization of nanoparticles in a liquid. In addition to biological samples also paints, pigments, sun creams, inks, metals, metal oxides or fuel additives in any non-corrosive solvent and water can be examined with virtually no sample preparation.

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U6-E06. Malvern Zetasizer Nano ZS particle size analyzer

Malvern Zetasizer Nano ZS particle size analyzer.

Description: The Zetasizer Nano ZS is a molecular and particle size, surface charge, and molecular weight measurement system based on static light scattering (SLS), dynamic light scattering (DLS), and electrophoretic light scattering (ELS). ). These are rapid, accurate and repeatable measurement methods that do not require large sample volumes and are non-destructive.
SLS determines the molecular weight from different concentrations of a sample by applying the Rayleigh equation.
DLS uses the Brownian motion of particles, which move randomly in a liquid. Through established theories, the speed of diffusion is related to size.
ELS combines light scattering with electrophoresis, converting electrophoretic mobility into a measure of zeta potential.

Technical specifications:

• Particle size:

  • Measurement angles: 90º
  • Measurement range: 0.3 nm – 10 µm
  • Max. concentration: 40 w/v
  • Buckets: polystyrene, glass, quartz
    • Zeta potential:
  • Size range: 3.8 nm – 100 µm
  • Max. concentration: 40 w/v
  • Max. conductivity: 260 mS/cm
  • Buckets: polystyrene
    • Molecular weight:
  • PM range: 300 Da – 20 mDa
  • Cuvette: quartz
    • System:
  • Detector: Avalanche photodiode
  • Laser: He-Ne (633 nm)
  • Temperature control range: 0º to 90º C

Applications:

• Molecular and particle size distribution analysis.
• Analysis of the stability or tendency of molecules or particles to aggregate, using zeta potential.
• Measurement of molecular weight.

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U6-E02. High-pressure phase analyzer for studying the thermodynamic behaviour of materials

High-pressure phase analyzer for studying the thermodynamic behaviour of materials

Description: Stainless steel vessel equipped with a sapphire windows for visual observation inside the vessel.

The equipment allows for a wide range of phase analysis, such as solubility and miscibility studies, with solids, liquids and gases at different range of pressures, up to 150 bar.

The vessel is equipped with a moving piston, driven by nitrogen at high pressure. The moving piston allows for a change in the effective volume of the vessel, allowing you to increase or decrease the amount of material inside the chamber during the phase analysis while maintaining isobaric conditions.

Technical Specifications:

  • Capacity: 29 to 55 mL
  • work pressure: 150 bar
  • work temperature: 50º C
  • Material: 316 Stainless steel
  • Gas: Nitrogen

Aplications:

  • Analysis of phases
  • Studies of solubility and miscibility
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U6-E01. High-pressure laboratory-scale plant with 50, 100 and 300 ml reactors for the processing of biomaterials

Description: The lab-scale high pressure equipment used to process materials with compressed fluids (i.e. CO2, ferons)

Technical Specifications: Lab-scale high pressure systems, based on a 50mL, 100 and a 300mL stirred high pressure autoclaves equipped with pumps for the supply of compressed fluids and liquid solutions, respectively. Both plants could also optionally be equipped with several filters, manometers, thermocouples and back pressure regulators. The maximum operative pressure is 23MPa and the maximum operative temperature is 200ºC.

The 300mL system is also equipped with a mass flow meter, and a data acquisition system.

The plants have been designed for micro- and nanostructuring molecular and soft materials.

Applications: Micro- and nanoparticulate single compounds with high supramolecular homogeneity (i.e. pure polymorphic phases, materials with single polymer folding, etc..)

Particulate polymeric matrix uniformly loaded with active compounds (therapeutics, cosmetic ingredients, catalyst, pigments and dyes, etc..)

Dispersed systems (suspensions, liposomes, emulsions, vesicles,) with narrow particle size distribution and high morphological homogeneity.

Porous materials, either crystalline or amorphous, with defined porosity and porous size.

 

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U26-E03. Bruker DRX500 spectrometer (11.7 T), and with three RF channels

11T NMR equipment with the following probes:

•• HR-MAS,
•• Cryoprobe, and
•• multinuclear probe with service for metabolomics for tissues, cell lines and biofluids.

Accessories:

  • BBOF Plus ATM. 1H/BB/19F direct multinuclear probe (5mm), with field gradients along the z axis, and automatic frequency tuning. Range of frequencies in the broadband channel from 15N to 31P.
  • TBI. 1H/BB/15N triple reverse probe (5mm), with field gradients along the z axis. Range of frequencies in the broadband channel from 15N to 31P.
  • BACS autosampler for 60 samples.
  • Accessory to control temperature, with air down to 5ºC. Liquid nitrogen evaporator for low temperature experiments.
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U26-E02. Microcamera for its use in the NM R equipment

Microcamera for its use in the NM R equipment for:

•• the simultaneous determination of structural images
(dimensions and sections of 50 μm and less)
•• metabolic images (voxel sizes < 200 μm) in model
systems.

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U26-E01. DRX-600 Bruker NM R equipment (14 Teslas)

DRX-600 Bruker NM R equipment (14 Teslas):

•• 4-channel electronic systems with applications in fluids, tissues, biomaterials and microimaging
•• Thermostating system for fluids and tissues, and for molecular imaging and microimaging
•• Set of coils: fluids 5 mm, micro-fluids 1 mm, tissues (High Resolution Magic Angle Spinning, HR-MAS) + pneumatic and microimaging system for 10, 5 and 2 mm.
•• 60 Amp GREAT unit for each X/Y/Z axis of the field gradients
•• 13C selective device with 1H decoupling.
•• 2D microcoil for 500 μm and 100 μm microsamples.
•• Refrigerated SampleJet autosampler with temperature control for 60 Samples

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U27-S01. Remote access to HPC

Remote access to HPC

The HPC service allows remote access to High Performance Computing, Massive Parallel Processing, Mass Storage and different software applications. Designed to meet the demands of projects requiring exceptional computational performance, our service provides users with the flexibility and power to address a wide variety of challenges. It responds to the increasing complexity of simulations carried out by the most advanced research projects.

Customer benefits

The “Remote Access to Infrastructure with Massively Parallel Processing in HPC” service offers our clients distinctive advantages that not only meet their requirements but also add significant value to their Research and Development projects. 

  • Exceptional Performance: We provide our clients with access to cutting-edge HPC infrastructure, ensuring exceptional computational performance. 
  • Flexibility for Various Applications: Our service is generic and highly adaptable, satisfying a wide variety of R&D applications. 
  • Elimination of Geographic Restrictions: By offering secure remote access to our infrastructure, we eliminate geographic limitations.

Essential Scenarios:

  • Cutting-edge Scientific Research: Our service is essential for projects that require significant computational power, such as detailed molecular dynamics simulations, biomedical and biochemical modeling, simulations of all types, etc. 
  • Development of High-Performance Algorithms: our service is crucial for testing and optimizing high-performance algorithms, ensuring efficient execution in production environments. 
  • Complex Data Analysis and Big Data: In projects that involve the analysis of large data sets, from genomic sequencing to artificial intelligence, our service allows for massively parallel processing, improving the speed and accuracy of the analysis.

Target customer

The service is designed to meet the specific needs of diverse user groups, allowing them to take full advantage of massively parallel processing capabilities. 

  • Scientific Researchers and Academics: We provide access to cutting-edge HPC infrastructure, allowing them to perform advanced simulations, complex modeling and data analysis at a scale that goes beyond the capabilities of conventional systems. 
  • High Performance Software Development Teams: Intensive algorithms and high-performance applications, we offer a scalable platform that facilitates extensive testing and optimization to ensure optimal performance. 
  • Biomedical Research Institutions: can leverage our infrastructure for the analysis of large data sets, detailed simulations and complex studies, driving significant advances in the understanding of diseases and the development of therapies. 
  • Artificial Intelligence and Machine Learning teams: can leverage our infrastructure for training complex models and analyzing massive data sets.

Additional information

The HPC service has more than 3260 cores and 5920 parallel processing threads, 26TB of RAM, 264TB NVMe and 400TB HDD of shared storage, all connected by a 100Gbps backbone network. In addition, we currently offer 251,392 CUDA cores, 720GB graphics memory, 1,179.42 peak FP16 TFLOPS, and 828.6 peak FP32 TFLOPS.

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U27-S02. Software installation on demand

Software installation on demand

This Unit offers an exceptional software installation service that is not present in our infrastructure. We study each case to try to find the best solution, as long as it fits the technical characteristics, both hardware and software of the Unit.

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U27-S03. Biomedical signals processing

Biomedical signals processing

In our continued commitment to providing advanced solutions in High-Performance Computing (HPC), we are proud to present our specialized service in “Biomedical Signal Processing”. This service harnesses the power of high-performance computing to facilitate the analysis and interpretation of biomedical signals, offering advanced solutions for a variety of clinical and research scenarios.
The HPC service allows remote access to High Performance Computing, Massive Parallel Processing, Mass Storage and different software applications. It responds to the increasing complexity of simulations carried out by the most advanced research projects.

Customer benefits

The “Biomedical Signal Processing” service offers our clients specific advantages by providing access to our advanced High-Performance Computing (HPC) infrastructure, adding significant value to your Research and Development (R&D) activities. Focusing on the critical scenarios in where our service becomes essential, we highlight the following advantages: 

  • Validation of Theoretical Models: We allow researchers to validate and adjust theoretical organ models through detailed simulations, using computing power to compare theoretical results with experimental data. 
  • Custom Algorithm Development: Researchers and scientists can leverage HPC infrastructure to develop and refine custom signal processing algorithms tailored to their specific research objectives. 
  • Analysis of Large Data Sets: For projects involving the analysis of large data sets of biomedical signals, we offer the processing power necessary to perform detailed evaluations and extract meaningful patterns.

Target customer

Access to our HPC infrastructure is designed to meet the needs of diverse user groups, allowing them to perform specialized calculations and experiments in the field of biomedical signal processing.

  • Researchers and Scientists: We offer biomedical engineering  researchers access to HPC resources to perform advanced simulations, validate theoretical models and explore new perspectives in the diagnosis and treatment of cardiac diseases.
  • Biomedical Algorithm Developers: For those focused on developing and refining specific signal processing algorithms, we provide the necessary infrastructure to implement and evaluate custom algorithms.
  • Healthcare Professionals and Biomedical Engineers: Healthcare professionals and biomedical engineers can use our HPC platform to analyze and process large signal data sets, improving efficiency in the analysis of clinical information and the development of advanced medical technologies.
  • Biomedical Technology Companies: We provide them with the ability to test and validate their products in simulated environments, optimizing the performance and precision of their solutions.

Additional information

The HPC service has more than 3260 cores and 5920 parallel processing threads, 26TB of RAM, 264TB NVMe and 400TB HDD of shared storage, all connected by a 100Gbps backbone network. In addition, we currently offer 251,392 CUDA cores, 720GB graphics memory, 1,179.42 peak FP16 TFLOPS, and 828.6 peak FP32 TFLOPS.

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