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2020 Rei Jaume I Awards ceremony – Laura Lechuga NANBIOSIS U4-

This monday 30 of october has taken place the traditional ceremony of Rei Jaume I Awards in Valencia, granted to six professionals in research, science and economics.

At the ceremony, the awards have been given to the winners of the six categories: Rei Jaume I Basic Research Prize 2020 to Fco. José García Vidal; Rei Jaume I Economy Prize 2020 to Diego Puga; Rei Jaume I Medical Research Prize 2020 to Miguel Beato del Rosal; Rei Jaume I Environmental Protection Award 2020 to Fernando T. Maestre; Rei Jaume I New Technologies Award 2020 to Laura Lechuga and Rei Jaume I Entrepreneur Award 2020 to Verónica Pascual.

Queen Letizia has led the event apologizing for the absence of King Felipe VI for being in quarantine, and had estated that the awards constitute “the example of how research, science, technology and entrepreneurship are the way that gives us as a society the tools to face challenges such as those that the pandemic has put on the table”. After, the Queen pointed out that “the talent, effort and generosity” of the winners of the Rei Jaime I Awards, one of the best endowed in Spain with 100,000 euros each discipline , show the ability to project a “modern, supportive and strong” Spain.Queen Letizia has emphasizes at the Rei Jaume I Awards that research is “essential” to face the pandemic.

The winners defend that the coronavirus has reaffirmed the importance of science and that the investment in science must be accompanied by a change in the model.

Laura Lechuga (New Technologies 2020 award), has called for a pact for science to provide stability because science requires long-term financing and structures, as well as decent salaries that prevent the brain drain that is formed with money public. “It is a millionaire loss,” she pointed out.

Prof. Laura M. Lechuga Gomez, full professor of the Spanish National Research Council (CSIC), head of the Nanobiosensors and Bioanalytical Applications group at the ICN2 and a member of the Networking Biomedical Research Centre (CIBER-BBN), received the New Technologies Award for her career in the field of photonic and phononic nanobiosensors. Prof. Lechuga is recently working on a EU funded project (CoNVaT) aiming to apply these technologies to develop a fast, portable and cheap device for the diagnostic of COVID-19.

Prof. Laura M. Lechuga has been recently awarded with the two most prominent scientific Prizes in Spain Rei Jaume I and the Spanish National Research Award.

The research group led by Laura Lechuga on Nanobiosensors and Bioanalytical Applications (NAnoB2A) from CIBER-BBN and ICN2-CSIC, coordinators of unit 4 ot NANBIOSIS ICTS have been folloing the Rei Jaume I awards ceremony in streaming, from the ICN2-CSIC, very proud of Laura Lechuga!

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Nb4D group- NANBIOSIS U2 receives the acreditation TECNICO, in the on line event organizes by ACCIO

Las November 27 was held the ACCIO ceremony (on line this year due to the Covid Pandemic restrictions) of disclosure of new TECNIO accreditations.

Aurea Rodriguez, Director of Business Innovation at ACCIO has welcomed the attendees to the event. Later, the TECNIO program Coordinator, Marta Peidro, presented the background and rationale for this accreditation for excellence groups in technology transfer in Catalonia. This year there have been five new groups from among all Catalan universities and research organizations, which have obtained the TECNIO accreditation for the first time, making a total of fifty-four groups accredited in 2020.

The event continued with the presentation of the five new accredited groups, starting with the IQAC-CSIC – CIBER-BBN Nb4D group, coordinator of NANBIOSIS unit 2 Custom Antibody Service (CAbS) that investigates improvements to current clinical diagnostic methods.

After the presentations of the five new groups, the tools and benefits that ACCIO offers to TECNIO groups were explained and the event ended with a round of questions from the attendees, such as what will be the future financing strategy of ACCIO for TECNIO groups or how has it been the response to the recent call for INNOTEC grants

As expressed by Prof M. Pilar Marco: “This seal recognizes us as a tech-transfer agent with distinguishing technological capabilities and increases our visibility in front of the business world.”

ACCIÓ is the agency set up by the Catalan Government to make Catalan enterprise more competitive throughout the world. Its key aims are to drive innovation, internationalisation and attract inward investment. ACCIÓ is enterprise-centred, working on the needs of each individual business and to work hand in hand to look for opportunities and achieve that all important competitive edge. At ACCIÓ we believe this edge can come about with work on three vital areas of competitive dynamics: innovation, internationalisatio, attraction of investment. ACCIÓ is a proactive agency, with a simple, clear and efficient modus operandi, above all dedicated to working in close quarters with enterprise. ACCIÓ is based in Barcelona with an international network of a further 35 Business Promotion Centres covering some 80 markets worldwide. It provides advice and practical help for businesses with a vocation to expand worldwide. It focuses on attracting inward investment into Catalonia and also works on synergies between R+D+i areas and business.

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U20-S015. Cytotoxicity: proliferation, LDH, apoptosis and ROS

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U20-S014. Hemocompatibility: hemolysis, platelet aggregation, plasma coagulation times and complement activation

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U20-S013. Detection of microbial (bacterial and mycoplasma) contaminationpre

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Two new equipment items at the U6 of Nanbiosis with cofinancing from FEDER funds

The U6 of NANBIOSIS (Biomaterial Processing and Nanostructuring Unit) has expanded its capabilities with 2 new equipment items for the characterization unit. Both equipment items will allow the characterization of some physico-chemical properties of different nanomaterials.

The Zetasizer ULTRA is used to measure the particle size of dispersed systems from sub-nanometer to several micrometers in diameter, using the technique of Dynamic Light Scattering (DLS). Zetasizer systems are also used to analyze particle mobility and charge (Zeta potential) using the technique of Electrophoretic Light Scattering (ELS), and the molecular weight of particles in solution using Static Light Scattering (SLS).

The Green laser module for the NanoSight NS300 equipment. The NS300 allows analysis of the size distribution and concentration of all types of nanoparticles from 0.01 – 1 µm in diameter. This new laser module will allow NTA to measure a range of fluorescent particles, avoiding interferences during the measurements due to sample (auto)fluorescence and absorption.  This is done by detecting the fluorescence signal, which is emitted naturally by particles or as a result of fluorescence labeling or tagging


This equipment have been confinanced by the European Regional Development Fund (ERDF) through the Plurirregional Operational Program of Spain (POPE)2014-2020

European Regional Development Fund
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The Nanomedicine Revolution

Yesterday, November, 25 took place, within the the program of the Ateneo of the EINA (School of Engineering and Architecture of Aragón), the online conference on “The Revolution of Nanomedicine” by Ramón Martínez Máñez.

The Conference chair, Jesús Martínez de la Fuente, Principal Investigator of the BIONANOSURF group of CIBER-BBN and the Institute of Nanoscience and Materials of Aragón, introduced the guest, Ramón Martínez Máñez, Scientific Director of CIBER-BBN, highlighting “his creativity in the use of his systems and how he combines them with different diagnostic release systems, combining organic chemistry, surface chemistry, applications in biotechnology and giving way to translation and transfer, his works are very unique“

Ramón Martínez Máñez, Scientific Director NANBIOSIS unit 26 NMR: Biomedical Applications II, gave a very instructive talke about what is nanotechnology and how nanotechnology revolution has reached the medicine, with current examples of the application of nanomedicines, as well as in the medicine of the future.

After it, a very interesting debate took place in which different issues were discussed, especially in relation to nanomedicine applied to therapy, such as the barriers to generalize the use of nanoparticles in therapy, the current state of implantation of nanoformulated drugs in the market and the advancement of the use of some nanoparticles as polymers or liposomes compared to inorganic nanoparticles, the degree of development of nanoparticles under GLP certification or why cancer is the main target of nanomedicine with a great difference over other pathologies. The audience asked questions that led to the discussion of some more controversial points such as whether it is true that “Big Pharma” does not like nanoparticles, why there is a regulatory vacuum regarding their use and how to solve these problems.

Regarding the diagnosis applications, Ramón Martínez commented that “nanotechnology already has its way open, both in the development of nanoparticles and systems to amplify the signal, based on nanophotonics, resonant rings or other technologies at the nanometric level. The pandemic has highlighted the importance of having rapid detection systems for bio parameters, pathogens, bacteria … We have a lot of knowledge acquired in recent years in these systems and they are currently being developed in a more or less short time, we are truly close to revolutionizing the field of detection“.

Finally, in realtion with the nanomedicine of the future, the questions raised in the debate revolved mainly around nanobots and their state of development or the problems that are emerging in it or the possibility of uniting nanomedicine with artificial intelligence and possible applications.

The Ateneo is an activity of the EINA in collaboration with the Aragón Engineering Research Institute and SAMCA Chair of Technological Development of Aragon, both directed by Pablo Laguna, Scientific Director of Nanbiosis U27 High Performance Computing. Pablo Laguna closed the event thanking Ramón Martínez Máñez and Jesús Martínez de la Fuente for their participation and highlighting the high number of attendees at the conference.

The conference can be followed in Spanish in EINA youtoube channel: https://www.youtube.com/watch?v=Y_Fh1O1VuNU

Anouncing this Conference in the Ateneo EINA, Ramón Martínez Máñez was yesterday interviewed by Aragon Radio. In this case, the interview had the focuss in the “Nanomedicine against COVID” . The podcast can be listen in Spanish here: https://www.cartv.es/aragonradio/podcast/emision/nanomedicina-frente-a-la-covid

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NANBIOSIS U12 expands its capabilities with a new SEM for morphological and dimensional characterization of solid samples

The U12 of NANBIOSIS (Nanostructured liquid characterization unit) has expanded its capabilities with a new equipment U12-E22. SEM Hitachi TM4000Plus II for morphological and dimensional characterization of solid samples

Low vacuum Scanning Electron Microscopy with two electron detectors (secondary, SE, and backscattered, BSE). SE imaging provides a detailed information of the morphology of the sample and BSE gives information about the different components of the sample, based on the different atomic number (the higher the atomic number, the brighter the surface).

The equipment can apply different vacuum levels (using a turbo molecular pump) with accelerating voltages between 5 and 20 kV and magnifications from 10x to 100,000x. Specimens with size up to 80 mm diameter and/or 50 mm thickness can be characterized and samples.

Conductive and non-conductive samples can be characterized with little or no previous preparation. The software enables image processing of micrographs, for instance, measuring the size of solid particles after the acquisition of images.

SEM analysis is very useful in several fields:

  • Life sciences, for the topographical and morphological characterization of tissues, hairs, fibers, etc.
  • Materials science, for quality control and failure analysis. Morphological properties are quite important in the research of innovative materials. In addition, the characterization of the surface is a key factor in porous materials used for delivery systems.
  • Semiconductor inspection and microchip assembly, to analyse the topography and to investigate the effectiveness of production methods.

The equipment has been financed by CSIC and with funds of the research group coordinanting the unit from CIBER-BBN and IQAC-CSIC, led by Carlos Rodriguez-Abreu

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U12-E22. SEM Hitachi TM4000Plus II for morphological and dimensional characterization of solid samples

U12-E22. SEM Hitachi TM4000Plus II for morphological and dimensional characterization of solid samples

Description:

Low vacuum Scanning Electron Microscopy with two electron detectors (secondary, SE, and backscattered, BSE). SE imaging provides a detailed information of the morphology of the sample and BSE gives information about the different components of the sample, based on the different atomic number (the higher the atomic number, the brighter the surface).

Appropriate vacuum levels are reached using a turbo molecular pump and electron beams are directed to sample specimens with accelerating voltages between 5 and 20 kV, which allow magnifications from 10x to 100,000x. Specimens with size up to 80 mm diameter and/or 50 mm thickness can be observed.

Conductive and non-conductive samples can be characterized with little or no previous preparation. The software enables image processing of micrographs, for measuring the size of solid particles after the acquisition of images.

Applications:

Topographical and morphological characterization of tissues, hairs, fibers, etc. Quality control and failure analysis. Morphological properties are quite important in the research of innovative materials. In addition, the characterization of the surface is a key factor in porous materials used for delivery systems. Semiconductor inspection and microchip assembly, to analyse the topography and to investigate the effectiveness of production methods.

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NANBIOSIS-ICTS AT CASEIB 2020

The XXXVII Annual Congress of the Spanish Society of Biomedical Engineering (CASEIB) is taking place between November 25 and 27. This new edition of CASEIB, in virtual format is organized by the CIBER-BBN group of Biomedical Engineering at Valladolid Universitiy, led by Prof. Roberto Sánchez Hornero.

Prof. Laura Lechuga, Scientific Director of NANBIOSIS U4 Biodeposition and Biodetection Unit, member of the advisoty committee of scientific experts (Multidisciplinary Working Group) to the Ministry of Science and Innovation in COVID-19 and coordinator of the European project CONVAT shall participate in the Roundtable I: Biomedical Engineering and COVID-19 November 26, 12:00 h

Researchers of BSICoS Group from CIBER-BBN and I3A-UZ, running NANBIOSIS U27 High Performance Computing, led by Prof. Pablo Laguna, will participate defending their last works:

  • “Delay between QT and RR in stress test records as an indicator of the heterogeneity of ventricular repolarization”. Cristina Pérez, Esther Pueyo, Juan Pablo Martínez, Jari Viik, Pablo Laguna.
  • “Prediction of sudden death in patients with chronic heart failure by studying the periodic dynamics of repolarization”. Saúl Palacios, Iwona Cygankiewicz, Antoni Bayés-de-Luna, Juan Pablo Martínez, Esther Pueyo.
  • “Electrodermal response analysis for the identification of patients with depression”. Marta Martínez, Jesús Lázaro, Spyridon Kontaxis, Pablo Laguna, Eduardo Gil, María Luisa Bernal Ruíz, Sara Siddi, Concepción de la Cámara, Jordi Aguiló, Esther García, Josep María Haro, Raquel Bailón.
  • “In silico characterization of the duration of repolarization and its variability in Type 1 Long QT syndrome under β adrenergic stimulation”. David Adolfo Sampedro-Puente, Fabien Raphel, Jesús Fernández-Bes, Pablo Laguna, Damiano Lombardi, Esther Pueyo
  • “Monitoring of Blood Potassium Concentration in dialysis through changes in the multi-lead morphology of the T wave: Comparison between using the transformation in Periodic and Principal Components”. Flavio Palmieri, Pedro Gomis, José Esteban Ruiz, Dina Ferreira, Alba Martin, Esther Pueyo, Pablo Laguna, Juan Pablo Martínez, Julia Ramírez.

Further information on BSICoS website

On the other hand researcher of NANBIOSIS at JUMISC will present:

  • “Study of the influence of the diameter and temperature of the nozzle on the thickness of the filament for bioprinting“. Enrique Mancha, Juan Carlos Gómez Blanco, Alfonso Carlos Marcos Romero, Manuel Matamoros Pacheco, Francisco Miguel Sánchez Margallo, José Blas Pagador Carrasco.
  • Influence of voluntary contractions on the basal sEMG activity of the pelvic floor muscles. M. Albaladejo-Belmonte, M. Tarazona, F.J. Nohales, J. Alberola-Rubio, J. Garcia-Casado
  • 3D Printing Mold Making: Soluble Male Viability for Hollow Artificial Organs Juan Carlos Gómez Blanco, José Blas Pagador Carrasco, Antonio Jesús Rodríguez Fuentes, Alfonso González González, Mara Olivares Marín, Jesús Usón Gargallo, Francisco Miguel Sánchez Margallo

Further information on JUMISC website

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