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Nanbiosis

Unit 1 of NANBIOSIS certified with ISO 9001: 2008

Unit 1 of NANBIOSIS, Production Platform Protein (PPP) at the Autonomous University of Barcelona, ​​directed by Dra. Neus Ferrer and coordinated by Professor Antonio Villaverde, provides the service of production and purification of recombinant proteins in different systems expression, microbial and non-microbial. This service was audited last November, based on the UNE EN ISO 9001: 2008 AENOR, who has issued a favourable certification report.

The requirements of this standard cover all aspects of management. This certification will expand and consolidate the service  that the Unit 1 of NANBIOSIS is giving to companies and public sector researchers and facilitate their integration in cooperative international projects.

AENOR is a Spanish company, renowned in national and international levels, in the development of standardization and certification activities. It was, in 1996 the first Spanish entity accredited by the National Accreditation Body (ENAC)

Nanbiosis_Unit 1 of NANBIOSIS certified with ISO 9001- 2008
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Graphene Flagship for Biomedical Tecnologies – Kick off meeting April 11-14 Barcelona

On April, 11-12 took place in Barcelona the kick off meeting of the new Graphene Flagship Work Package devoted to Biomedical Technologies, one emerging application area for graphene and other 2D materials. The Kick-off event, was co-organised by Dr. Rosa Villa (CNM-IMB-CSIC, CIBER-BBN) Scientific Coordinator of Unit 8 of NANBIOSIS (in the center of the first row in the photo). More than 35 Scientifics from 14 research groups attended to the meeting

The Graphene Flagship, the EU’s biggest ever research initiative, involves the coordination research of over 150 partners from more than 20 European countries withing a timeframe of 10 years. This project is implemented as a total of 15 research Work Packages on specific science and technology topics. The new Work Package will focus on the development of implants based on graphene and 2D-materials with therapeutic functionalities for specific clinical outcomes in neurology, ophthalmology and surgery, between other disciplines that will be further developed in the next phases of the Graphene Flagship.

The launch meeting held on 11 and 12 April in the Convalescence House of the Autonomous University of Barcelona (UAB), was co-organized by the ICN2, the National Microelectronics Centre (CNM-IMB-CSIC, CIBER-BBN; researcher Dr. CSIC. Villa Rosa) and IDIBAPS. This meeting began with two lectures given by well known neuroscientists, Dr. Gerardo Conesa, chief of neurosurgery at the Hospital del Mar (Barcelona) and Dr. Xavier Navarro,  the Institute of Neurosciences at the UAB and belonging to CIBERNED.

Nanbiosis_U8_Graphene Flagship for Biomedical Tecnologies
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Esther Pueyo nominated for the awards Aragonese of the Year 2015 for her research on aging heart, carried through the computational capabilities of Unit 27 of NANBIOSIS  

Esther Pueyo, researcher at the group of CIBER-BBN, BSICoS, which coordinates Unit 27 of NANBIOSIS, has been nominated for awards Aragonese of the Year  in the category of science and research. Esther develops a project considered of reference by European Union that studies aging heart through mathematical and computational tools combined with experimental and clinical work aimed at proposing new markers of risk for arrhythmias.

The Newspaper El Periódico de Aragon calls for the twenty second consecutive year Aragonese of the Year, a competition that recognizes the personal and professional Aragonese citizens and groups who develop their work in different fields, always with social significance merits.

The Aragonese of the Year contest is divided into five categories, with four nominations each. One that gets the most votes will rise to the Aragonese Year award in the cathegories: Company, Sports, Human Values, Science and Research and Culture

Esther Pueyo (U27 Nanbiosis) nominated for Aragonese of the Year 2015 for her research on aging heart
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NANOMOL-CSIC of CIBER-BBN is one of the 54 accredited institutions in Catalonia with the new TECNIO seal

At an event held on April 7th 2016 chaired by Hon. Mr. Jordi Baiget, Minister for Business and Enterprise of the Generalitat of Catalonia, were presented the first 54 organizations accredited with the TECNIO seal; one of which was NANOMOL-CSIC, the research group of CIBER-BBN coordinating Unit 6 of NANBIOSIS.

The accreditation is the hallmark TECNIO granted by the Government of Catalonia, through ACCIÓ to identify the developers and facilitators of differential technologies in Catalonia.

Nanbiosis-U6 -NANOMOL-CSIC of CIBER-BBN accredited with TECNIO seal
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Josep Samitier, Scientific Director of Unit 7 of NANBIOSIS, was named new president of the Associació Catalana d’Entitats de Recerca (ACER).

Associació Catalana d’Entitats de Recerca (ACER) is an independent association of more than 40 institutions in Catalonia – including CRG, IRB, ICFO, IBEC, VHIR and IDIBAPS – which conduct research as their principal mission. The collective vocation of the associated organisations is to contribute to defining the scientific and research priorities and policies in Catalonia, and to optimise their management and implementation in their respective areas  by representing its associated centres, encouraging collaboration and the coordinated exchange of information, promoting synergies with similar agencies related to local, national or international research, and contributing to the improvement of scientific understanding in society.

The Director’s Board, (in the picture) is the chartered body that rules, manages, administrates and represents the association, and its members are chosen by the General Assembly. The President and Secretary of ACER are also those of the Board, and are chosen by the General Assembly from among its members.

Josep Samitier, Scientific Director of Unit 7 of NANBIOSIS_named new president of ACER
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Government of Aragón, Spain, paid tribute to the seven scientists who have a grant of European excellence and develop their projects at the University of Zaragoza: Jesús Santamaría, Diego Gutierrez, Igor Irastorza, Esther Pueyo, Manuel Arruebo, José Manuel García Aznar and Jesús Martínez de la Fuente.

President of the Government of Aragon, Javier Lambán, has personally expressed his gratitude and appreciation for the work of seven researchers from the University of Zaragoza who have been granted with projects of excellence funded by the European Research Council.

Jesús Santamaría, Scientific Director of Unit 9 of NANBIOSIS, with an Advanced Grant funded with 1.85 million euro, is working on a project to develop a microreactor that enables the industry to save energy and raw materials.

Esther Pueyo, member of the research group BSICoS of CIBER-BBN, which coordinates Unit 27 of NANBIOSIS, has a Starting Grant of 1.5 million and is studying the aging of the heart to propose new markers of risk for arrhythmias in the aging population.

Manuel Arruebo member of the research group Nanostructured films and particles of CIBER-BBN, which coordinates Unit 9 of NANBIOSIS, with a Grant Consolidator 1.5 million for the project Nanohedonism, develops injectable nanoparticles created with microfluidic reactors for the controlled and remote delivery of drugs in the treatment of chronic pain.

 

Nanbiosis_U27_U9_Three researchers of NANBIOSIS among the seven Aragonese scientists granted with an ERC.
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Ramon Martinez Mañez, Scientific Director of Unit 26 of NANBIOSIS, has participated in the development of  new nanodevices that allow the controlled release of drugs, namely doxorubicin, for therapies against breast cancer.

So far, the work has focused on cellular assays, with positive results, that could open new ways to improve the effectiveness of some drugs used in the treatment of breast cancer.

The main novelty of these nanodevices is that the molecule covering the nanodevice not only controls when the transported drugs are released, but also controls where they are released to direct them to cells expressing TLR3, a protein of the innate immune system overexpressed in some cell lines of breast cancer. Through this protein it is also launched a death signal that ends with the tumor cell.

Their study was published last January in Chemistry-A European Journal:

Ultimo A, Giménez C, Bartovsky P, Aznar E, Sancenón F, Marcos MD, Amorós P, Bernardo AR, Martínez-Máñez R, Jiménez-Lara AM, Murguía JR.Targeting Innate Immunity with dsRNA-Conjugated Mesoporous Silica Nanoparticles Promotes Antitumor Effects on Breast Cancer Cells. Chemistry. Chemistry – A European Journal. DOI: 10.1002/chem.201504629

Nanbiosis_U26_New nanodevices to improve therapy for breast cancer
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The Scientific Director and the Coordinator of NANBIOSIS, Jaume  Veciana and Jesús Izco, were invited by Professor Stefano Geuna (Professor of Human Anatomy at the Department of Clinical and Biological Sciences of the University of Torino) last 9th of March 2016 to present the CIBER-BBN, its scientific program and  its technologies to researchers of l’Università di Torino, in order to explore the possibilities of collaboration between the two institutions and promoting joint projects.

The meeting took place at the Molecular Biotechnology Center of the Molecular Biotechnology and Health Science department (www.mbc.unito.it/en ). The audience was made up of members representing six departments such as Department of Molecular Biotechnology and Health Sciences, Department of Neurosciences or the Department of Medical Sciences among others. After the presentations, up to ten face to face meetings were organized with research groups and staff of the Internalization Office from different departments to look for synergies and find out ways of collaboration. Topics such as nanoencapsulation for drug delivery, functionalization of biomaterials for regenerative medicine, especially for nerve regeneration or cell therapy for cancer were discussed and many common interests were detected. Following up the meeting, several actions were agreed and some of them have been already initiated to start new collaborations between both institutions.

L’Università di Torino is actively developing biotechnologies in the field of biomedical sciences, with specific focus on the study of the molecular mechanisms at the basis of physiopathological processes that have a great impact on human health, such as cardiovascular diseases, inflammation, stem cell biology and cancer. These researches are based on experimental work carried out by the biomedical departments of l’ Università di Torino.

Nanbiosis U6_Partnering opportunities with l’Università degli studi di Torino 9March2016
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Elisabet Prats is a young scientist, researcher at Biomonitoring group of CIBER-BBN and  CNM, which coordinates Unit 8 of NANBIOSIS, and a science disseminator with comedian monologues at “Big Van”.

[Elisabet Prats in Informativos.net]

As a science disseminator, Elisabet has recently appeared in media and forums explaining the progress made by her research group in the European project Graphene Flagship. For example, a graphene sensor to detect brain electrical activity, successfully presented at Mobile World Congress. Elisabet clearly explains “We are able to measure the electrical signals of the brain with graphene, graphene due to its versatility, allows the reduction in size of the sensors, giving much more information to the doctor” and describes a future in which “we shall control mechanical arms with brains implants”.

Nanbiosis_U8 - Biomedical applications of graphene, Elisabet Prats in Informativos.net
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Recently, the COST Action EURELAX CA15209 "European Network on NMR Relaxometry" has been approved. In this action, Jose Javier Serrano, Scientific Coordinator of Unit 15 of NANBIOSIS, has been directly involved as Secondary Proposer.

The “European Network on NMR Relaxometry” Action aims to develop a research network focused on NMR relaxometry for fundamental and applied sciences concerned with the molecular dynamics of soft and hard matter. NMR relaxometry possesses the unique ability to reveal the mechanisms of molecular motion and their characteristic times over a huge range of time scales from picosecond to millisecond, with selectivity in probing the dynamics of molecular and ionic species. This potential of NMR relaxometry will be developed with applications in advanced materials science and industry, medical diagnostics and therapeutics, agri-food and environmental science and technologies. This research is intrinsically related to progress in the understanding of spin relaxation phenomena and in technological development, as both components form the basis for the fundamental and technology-oriented research employing NMR relaxometry.

NMR relaxometry is a scientific and technological asset of Europe. The joint efforts of scientists across numerous disciplines (chemistry, physics, materials science and others), of medical doctors and engineers, regrouped through the networking means provided by this Action, will allow the efficient exploitation of NMR relaxometry in fields that are currently key challenges for Europe, such as early disease detection, energy sources and storage, advanced tuneable materials, food quality, soil fertility, water and sediment performance.

The Action will play a seminal role in facilitating links between the scientific and industrial communities for knowledge exchange and technology transfer to stimulate cross-disciplinary innovations, educating the next generation of talented researchers and developing the full potential of NMR relaxometry in Europe.

 

Nanbiosis U15_Secondary Proposer in COST Action European Network on NMR Relaxometry_Coord.Jose Javier Serrano
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