U12-E07. SITE Spinning Drop Interfacial Tensiometer
Description:
Instrument for determination of liquid-liquid interfacial tensions by the spinning drop method
Applications:
Determination of ultra-low interfacial tensions (up to 10-5 mN.m-1) in colloidal liquid-liquid biphasic systems at controlled temperature.
U12-E06. S3 Micro SAXS/WAXS Small and Wide Angle X-Ray Spectrometer
Description:
S3 MICRO instrument (Hecus X-ray Systems, Graz, Austria) for determinations of X-ray scattered intensity as a function of scattering angle. This instrument is equipped with a GENIX microfocus X-ray source and a FOX 2D point-focusing element (both from Xenocs, Grenoble). It can measure simultaneously at small angle (0,2º-8º) and wide angle (18º-28º).
Applications:
Structural characterization of materials within the nanometer range. This includes determination of symmetry, morphology, characteristic size, fractal dimension and surface area. These studies can be applied to liquid crystals, micellar aggregates, mesoporous materials, nanoparticles, proteins and nanostructured films.
U12-E05. Mastersizer 2000 Light Diffractometer
Description:
Instrument Mastersizer 2000 that measures by means of laser diffraction the size and distribution of particles or droplets in suspension. It is equipped with a liquid dispersing unit for small volume (Hydro 2000G) to measure emulsions, dispersions, etc. and a solid dispersion unit (Scirocco) to analyse dried powders. It is equipped with a software (windows operated) for the data processing to obtain the characteristic size (droplet, particle) and its distribution.
Applications:
Determination of the droplet/particle diameter for emulsions, suspensions and solid samples (powder) in the range of 100 nm – 2000 mm. The results are expressed in standard percentiles D(v,0.1), D(v0.5), D(v0.9), mean volume diameter (D[4,3]), mean surface diameter (Sauter mean diameter, D[3,2]), specific surface area (SSA), etc.
U12-E03. AR-G2 Rheometer
Description:
Rheometer with magnetic bearings which allows measuring torques down to 0.003 N.m. It can perform either stress controlled or strain controlled measurements. The angular velocity range is 2×10-7 to 628 rad/s. The maximum measurable torque is 200 mN.m, with a resolution of 0.1 nN.m. Several geometries are available, such as concentric cylinders, cone-plate, plate-plate (different sizes) and also cross hatched plates which are suitable to measure gel samples. Temperature is controlled with a Peltier system (from -20ºC to 200ºC) and with a Upper heating plate device. There is also an interfacial rheometry accessory. The instrument’s software enables to perform a wide variety of tests and analyses.
Applications:
Determination of viscosities from flow curves (stress vs shear rate); estimation of storage (elastic) modulus and loss (viscous) modulus, creep assays, temperature ramps; Determination of gel and glass points; Estimation of interfacial viscosity and moduli.
U12-E02. CytoViva Hyperspectral Imaging System (HSI)
Description:
The instrument combines enhanced dark field optical microscopy with high resolution spectral imaging. These integrated technologies have been designed to allow optical observation and spectral characterization of nanomaterials and cell matrices. There is no need of sample preparation in advance or fluorescent labeling to observe or characterize spectroscopically nanomaterials in complex media.
Applications:
Quantitative spectral analysis of nanomaterials, characterization of surfaces and functional groups bound to nanomaterials, spectral characterization of biological samples .
U12-E01. 3D cross-correlation dynamic light scattering (DLS) spectrometer
Description:
Photon Correlation Spectrometer (PCS) for dynamic (DLS) and static (SLS) light scattering measurements for angles in the 20-140º range and capacity of suppressing multiple scattering thanks to the 3D-cross correlation technology (down to 5% of transmission for sub-micrometer sample thickness). The instrument is equipped with a He-Ne laser and its software allows the estimation of particle size by Cumulant or CONTIN analysis. It is also possible to measure non-ergodic samples with a rotating sample holder.
Applications:
Determination of particle size and shape, size distribution, etc. in colloid systems (e.g. solid dispersions, micelles, microemulsions, nano-emulsions, polymers, vesicles or liposomes) Estimation of molecular weight of polymers and interaction parameters (e.g. second virial coefficient). Estimation of gel transitions.
Nano eNabler™ System equipped with an outer enclosure to completely control de environment (Humidity range: 25-80% RH). Optical Microscope (150X to 1000X) with Video Capture controlled with the NanoWare™ software. A Bioforce UV Tip Cleaner for cleaning of the SPT™ for further reuse is also available.
System specifications:
•• Delivery of attoliter (10-15 L) to femtoliter (10-18 L) volumes
•• Printing of spots and lines from 1 to 60 μm
•• 20 nm stage resolution, 50 mm XY travel range
•• 100 msec printing cycle
•• 25 to 80% Relative Humidity (RH) work range
•• High control of the dispensed volume and the size of the formed drop
•• Printing in any user defined-pattern
•• Multiplexing ability
›› Compatible materials for deposition:
•• Antibodies and other proteins
•• Nucleic acids
•• Viruses
•• Cells, bacteria
•• Nanoparticles (e.g. Quantum dots, colloidal nanoparticles…)
•• Etchants, solvents, adhesives
›› Compatible surfaces:
•• Glass, silicon, silanes
•• Alkanethiol, SAMs
•• Gold and other metals
•• Hydrogels
•• Nitrocellulose
•• PDMS
•• Plastic and other polymers
For determination of size distribution in the 1-1000 nm range, we offer a Photon Correlation Spectrometer (PCS) for dynamic (DLS) and static (SLS) light scattering measurements for angles in the 20-140º range and capacity of suppressing multiple scattering thanks to the 3D-cross correlation technology (down to 5% of transmission for sub-micrometer sample thickness). The instrument is equipped with a He-Ne laser and its software allows the estimation of particle size by Cumulant or CONTIN analysis. It is also possible to measure non-ergodic samples with a rotating sample holder.
For determination of size distribution in the 100-10,000 nm range we offer a Mastersizer 2000 instrument that measures by means of laser diffraction the size and distribution of particles or droplets in suspension. It is equipped with a liquid dispersing unit for small volume (Hydro 2000G) to measure emulsions, dispersions, etc. and a solid dispersion unit (Scirocco) to analyse dried powders. It is equipped with a software (windows operated) for the data processing to obtain the characteristic size (droplet, particle) and its distribution.
Customer benefits
The services provided by the unit are very relevant for product formulation and quality control. Applications include determination of the droplet/particle diameter for emulsions, suspensions and solid samples (powder) in the range of 100 nm – 2000 mm. The results are expressed in standard percentiles D(v,0.1), D(v0.5), D(v0.9), mean volume diameter (D[4,3]), mean surface diameter (Sauter mean diameter, D[3,2]), specific surface area (SSA), etc.
Target customer
Public research organisations, academia and industry in the pharmaceutical, chemical, food and cosmetic sectors.
Additional information
More information can be found at https://www2.iqac.csic.es/qci/
For this service, we offer a S3 MICRO instrument (Hecus X-ray Systems, Graz, Austria) for determinations of X-ray scattered intensity as a function of scattering angle. This instrument is equipped with a GENIX microfocus X-ray source and a FOX 2D point-focusing element (both from Xenocs, Grenoble). It can measure simultaneously at small angle (0,2º-8º) and wide angle (18°-28°).
We also offer a Quantachrome Autosorb iQ-AG equipment that provides gas adsorption/desorption curves, for the calculation of specific surface area and pore size analysis. This equipment allows the simultaneous degassing of two samples and the physisorption analysis of a third sample, at relative pressures above P/P0 > 1×10-3. The gas sorption analyzer is equipped with a cryogenic dewar for measurements until 90 hours.
Customer benefits
The services provided by the unit are very relevant for product formulation and quality control. Applications include structural characterization of materials within the nanometer range. This includes determination of symmetry, morphology, characteristic size, fractal dimension and surface area. These studies can be applied to liquid crystals, micellar aggregates, mesoporous materials, nanoparticles, proteins and nanostructured films. Also characterization of the porosity and surface area of nanoparticles, macroporous, macro/mesoporous and mesoporous materials like aluminas, silicas and other materials including M41S materials (eg. MCM-41), PMOs, KITs and many SBAs.
Target customer
Public research organizations, academia and industry in the pharmaceutical, chemical, food and cosmetic sectors.
Additional information
More information can be found at https://www2.iqac.csic.es/qci/
This is an integrated service in which we offer the determination of the phase behaviour (e.g. as a function of temperature and concentration) of surfactants and polymers using different characterization techniques such as SAXS and polarized optical microscopy.
Customer benefits
The services provided by the unit are very relevant for product formulation and quality control.
Target customer
Public research organizations, academia and industry in the pharmaceutical, chemical, food and cosmetic sectors.
Additional information
More information can be found at https://www2.iqac.csic.es/qci/
