Planing, execution and interpretation of in vivo assays requirestime and expertise. At this unit, we give consultancy serviceson preclinical model design, support and advice for research projects, including selection and use of the appropriate imaging system and evaluation and interpretation of the data obtained.
The unit/platform is specialized in oncology and lysosomal storages diseases, and several animal models are available for this type of diseases.
However, we are experienced in developing new efficacy models for testing novel nanomaterials, carriers and therapeutica compounds. Please contact us to see how we can help you in your research Project.
Potential target toxicity of new nanomaterials and drug delivery systems has to be carefully evaluated to support further clinical assays. At U20 we can design, perform and evaluate all type of toxicological studies, including those toxicity analyses performed along with efficacy studiestomore specifically designed long-term or short-term toxicity assays.
Specifically, we provide full services of anatomical pathology, from sample preparation, inclusion, section and staining to anatomopathological evaluation.
This service is responsible for conducting regulatory preclinical studies for the pharmaceutical industry and interested companies. Among the studies that can be carried out are: in vivo toxicity studies, local and systemic tolerance and efficacy studies. Pharmacokinetic studies, dosage studies of test products and biocompatibility studies of new drugs and medical devices are also performed.
Customer benefits
These studies are carried out under strict quality regulations, certified with ISO-9001 and Good Laboratory Practices (GLP), quality standards that allow the production of high-precision results.
Therefore, preclinical studies can be carried out in compliance with the strict guidelines of regulatory agencies, ensuring the reliability and traceability of all results and tests carried out in their different services.
Target customer
The services offered may be of interest to different companies and laboratories that work within the pharmaceutical industry. Companies whose objective is to test possible candidates for molecules, drugs or medical devices.
References
One hall for the reception and handling of animals.
2 quarantinerooms pre-experimental process
Room to perform small procedures and cures and preparation rooms for large animals prior to the surgical area
Four multi-use rooms for maintenance of rodents and lagomorphs.
Lagomorphs can individually accommodate upto 102 rabbits.
One barrier zone for rodents maintenance under SPF conditions with capacity for about 3,000 animals in microisolators. It has autoclaves, SAS to the material inlet, automatic beverage system by reverse osmosis, laminar flow hoods for animal handling and integrated operating room within the barrier zone.
One barrier zone for rodents maintenance under SPF conditions with capacity for about 3,000 animals in microisolators. It has autoclaves, SAS to the material inlet, automatic beverage system by reverse osmosis, laminar flow hoods for animal handling and integrated operating room within the barrier zone.
